A multiplexed, automated evolution pipeline enables scalable discovery and characterization of biosensors
Biosensors are key to engineered biological systems. Here the authors demonstrate rapid de novo in vitro evolution of RNA biosensors of small molecules in a fully automated system.
Guardado en:
Autores principales: | Brent Townshend, Joy S. Xiang, Gabriel Manzanarez, Eric J. Hayden, Christina D. Smolke |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/2049eb336bef4898b46560e95fa9af7a |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Scalable synthesis enabling multilevel bio-evaluations of natural products for discovery of lead compounds
por: Lizhi Zhu, et al.
Publicado: (2018) -
Synthetic Gene Circuits Enable Systems-Level Biosensor Trigger Discovery at the Host-Microbe Interface
por: Alexander D. Naydich, et al.
Publicado: (2019) -
A high-throughput pipeline for scalable kit-free RNA extraction
por: Ping Han, et al.
Publicado: (2021) -
Performance metrics and enabling technologies for nanoplasmonic biosensors
por: Sang-Hyun Oh, et al.
Publicado: (2018) -
Automated multiplex genome-scale engineering in yeast
por: Tong Si, et al.
Publicado: (2017)