Structure and mechanism of DNA delivery of a gene transfer agent

Gene transfer agents (GTAs) are phage-like particles that mediate lateral gene exchange. Here, the authors provide the structure of the GTA of Rhodobacter capsulatus (RcGTA), which resembles a tailed phage, and describe the conformational changes required for DNA ejection.

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Autores principales: Pavol Bárdy, Tibor Füzik, Dominik Hrebík, Roman Pantůček, J. Thomas Beatty, Pavel Plevka
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/205d0c3e3d524f7a8f245523800b58b3
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Sumario:Gene transfer agents (GTAs) are phage-like particles that mediate lateral gene exchange. Here, the authors provide the structure of the GTA of Rhodobacter capsulatus (RcGTA), which resembles a tailed phage, and describe the conformational changes required for DNA ejection.