Structure and mechanism of DNA delivery of a gene transfer agent
Gene transfer agents (GTAs) are phage-like particles that mediate lateral gene exchange. Here, the authors provide the structure of the GTA of Rhodobacter capsulatus (RcGTA), which resembles a tailed phage, and describe the conformational changes required for DNA ejection.
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Nature Portfolio
2020
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oai:doaj.org-article:205d0c3e3d524f7a8f245523800b58b32021-12-02T17:39:44ZStructure and mechanism of DNA delivery of a gene transfer agent10.1038/s41467-020-16669-92041-1723https://doaj.org/article/205d0c3e3d524f7a8f245523800b58b32020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16669-9https://doaj.org/toc/2041-1723Gene transfer agents (GTAs) are phage-like particles that mediate lateral gene exchange. Here, the authors provide the structure of the GTA of Rhodobacter capsulatus (RcGTA), which resembles a tailed phage, and describe the conformational changes required for DNA ejection.Pavol BárdyTibor FüzikDominik HrebíkRoman PantůčekJ. Thomas BeattyPavel PlevkaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020) |
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Science Q |
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Science Q Pavol Bárdy Tibor Füzik Dominik Hrebík Roman Pantůček J. Thomas Beatty Pavel Plevka Structure and mechanism of DNA delivery of a gene transfer agent |
description |
Gene transfer agents (GTAs) are phage-like particles that mediate lateral gene exchange. Here, the authors provide the structure of the GTA of Rhodobacter capsulatus (RcGTA), which resembles a tailed phage, and describe the conformational changes required for DNA ejection. |
format |
article |
author |
Pavol Bárdy Tibor Füzik Dominik Hrebík Roman Pantůček J. Thomas Beatty Pavel Plevka |
author_facet |
Pavol Bárdy Tibor Füzik Dominik Hrebík Roman Pantůček J. Thomas Beatty Pavel Plevka |
author_sort |
Pavol Bárdy |
title |
Structure and mechanism of DNA delivery of a gene transfer agent |
title_short |
Structure and mechanism of DNA delivery of a gene transfer agent |
title_full |
Structure and mechanism of DNA delivery of a gene transfer agent |
title_fullStr |
Structure and mechanism of DNA delivery of a gene transfer agent |
title_full_unstemmed |
Structure and mechanism of DNA delivery of a gene transfer agent |
title_sort |
structure and mechanism of dna delivery of a gene transfer agent |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/205d0c3e3d524f7a8f245523800b58b3 |
work_keys_str_mv |
AT pavolbardy structureandmechanismofdnadeliveryofagenetransferagent AT tiborfuzik structureandmechanismofdnadeliveryofagenetransferagent AT dominikhrebik structureandmechanismofdnadeliveryofagenetransferagent AT romanpantucek structureandmechanismofdnadeliveryofagenetransferagent AT jthomasbeatty structureandmechanismofdnadeliveryofagenetransferagent AT pavelplevka structureandmechanismofdnadeliveryofagenetransferagent |
_version_ |
1718379811774136320 |