Promoter-wide hypermethylation of the ribosomal RNA gene promoter in the suicide brain.

Promoter-wide hypermethylation of the ribosomal RNA gene promoter in the suicide brain.

<h4>Background</h4>Alterations in gene expression in the suicide brain have been reported and for several genes DNA methylation as an epigenetic regulator is thought to play a role. rRNA genes, that encode ribosomal RNA, are the backbone of the protein synthesis machinery and levels of r...

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Autores principales: Patrick O McGowan, Aya Sasaki, Tony C T Huang, Alexander Unterberger, Matthew Suderman, Carl Ernst, Michael J Meaney, Gustavo Turecki, Moshe Szyf
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2008
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/20644e04490b4354bc9a449488f38d1a
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