Viral quasispecies assembly via maximal clique enumeration.

Virus populations can display high genetic diversity within individual hosts. The intra-host collection of viral haplotypes, called viral quasispecies, is an important determinant of virulence, pathogenesis, and treatment outcome. We present HaploClique, a computational approach to reconstruct the s...

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Bibliographic Details
Main Authors: Armin Töpfer, Tobias Marschall, Rowena A Bull, Fabio Luciani, Alexander Schönhuth, Niko Beerenwinkel
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2014
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Online Access:https://doaj.org/article/2064e6e3f9d348efb334daaae6663cd3
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