A non-invasive far-red light-induced split-Cre recombinase system for controllable genome engineering in mice

A non-invasive far-red light-induced split-Cre recombinase system for controllable genome engineering in mice

Current light-inducible Cre-loxP systems have minimal capacity for deep tissue penetration. Here, the authors present a far-red light-induced split Cre-loxP system for in vivo genome engineering.

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Autores principales: Jiali Wu, Meiyan Wang, Xueping Yang, Chengwei Yi, Jian Jiang, Yuanhuan Yu, Haifeng Ye
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/2076496f888c4b9ea4217dc63cfc68ab
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spelling oai:doaj.org-article:2076496f888c4b9ea4217dc63cfc68ab2021-12-02T16:26:25ZA non-invasive far-red light-induced split-Cre recombinase system for controllable genome engineering in mice10.1038/s41467-020-17530-92041-1723https://doaj.org/article/2076496f888c4b9ea4217dc63cfc68ab2020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17530-9https://doaj.org/toc/2041-1723Current light-inducible Cre-loxP systems have minimal capacity for deep tissue penetration. Here, the authors present a far-red light-induced split Cre-loxP system for in vivo genome engineering.Jiali WuMeiyan WangXueping YangChengwei YiJian JiangYuanhuan YuHaifeng YeNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jiali Wu
Meiyan Wang
Xueping Yang
Chengwei Yi
Jian Jiang
Yuanhuan Yu
Haifeng Ye
A non-invasive far-red light-induced split-Cre recombinase system for controllable genome engineering in mice
description Current light-inducible Cre-loxP systems have minimal capacity for deep tissue penetration. Here, the authors present a far-red light-induced split Cre-loxP system for in vivo genome engineering.
format article
author Jiali Wu
Meiyan Wang
Xueping Yang
Chengwei Yi
Jian Jiang
Yuanhuan Yu
Haifeng Ye
author_facet Jiali Wu
Meiyan Wang
Xueping Yang
Chengwei Yi
Jian Jiang
Yuanhuan Yu
Haifeng Ye
author_sort Jiali Wu
title A non-invasive far-red light-induced split-Cre recombinase system for controllable genome engineering in mice
title_short A non-invasive far-red light-induced split-Cre recombinase system for controllable genome engineering in mice
title_full A non-invasive far-red light-induced split-Cre recombinase system for controllable genome engineering in mice
title_fullStr A non-invasive far-red light-induced split-Cre recombinase system for controllable genome engineering in mice
title_full_unstemmed A non-invasive far-red light-induced split-Cre recombinase system for controllable genome engineering in mice
title_sort non-invasive far-red light-induced split-cre recombinase system for controllable genome engineering in mice
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/2076496f888c4b9ea4217dc63cfc68ab
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