Nasal-type NK/T-cell lymphoma in a patient with hidradenitis suppurativa: A case report

Background: Nasal-type NK/T-cell lymphoma is a rare but deadly form of non-Hodgkin's lymphoma that initially presents with local symptoms including erythema, swelling, and epistaxis. Due to misdiagnosis and improper treatment with antibiotics, this tumor will frequently expand to involve nearby...

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Autores principales:	Clara M. Kerwin, Anne E. Getz
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Nasal-type NK/T-cell lymphoma Hidradenitis suppurativa Misdiagnosis Hard palate erosion Otorhinolaryngology RF1-547
Acceso en línea:	https://doaj.org/article/207fa4f476b548cfbb22ff9f9f6cda35
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spelling	oai:doaj.org-article:207fa4f476b548cfbb22ff9f9f6cda352021-11-18T04:50:55ZNasal-type NK/T-cell lymphoma in a patient with hidradenitis suppurativa: A case report2468-548810.1016/j.xocr.2021.100379https://doaj.org/article/207fa4f476b548cfbb22ff9f9f6cda352021-11-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S246854882100120Xhttps://doaj.org/toc/2468-5488Background: Nasal-type NK/T-cell lymphoma is a rare but deadly form of non-Hodgkin's lymphoma that initially presents with local symptoms including erythema, swelling, and epistaxis. Due to misdiagnosis and improper treatment with antibiotics, this tumor will frequently expand to involve nearby facial bones and the oropharynx, with characteristic erosion of the hard palate. Even with treatment, mortality rates are high. We present a case of Nasal-type NK/T-cell lymphoma in a patient whose disease was initially attributed to his pre-diagnosed hidradenitis suppurativa (HS). Case description: A 38-year old male presented with several weeks of progressive nasal swelling and redness, which he initially attributed to his pre-existing HS and self-treated with antibiotics. The patient was subsequently prescribed several courses of increasingly broad-spectrum antibiotics without improvement in his symptoms. Alternative non-infectious diagnoses were only given strong consideration once the tumor had grown to involve nearby structures including the maxilla, nasal sinuses, and oropharynx with characteristic erosion of the hard palate. Conclusions: Nasal-type NK/T-cell lymphoma is a rare and frequently misdiagnosed disease that can cause progressive morbidity and death if not properly treated. A broad differential should be maintained when evaluating prolonged nasal inflammation without systemic signs of infection, particularly when symptoms do not improve with antibiotic therapy.Clara M. KerwinAnne E. GetzElsevierarticleNasal-type NK/T-cell lymphomaHidradenitis suppurativaMisdiagnosisHard palate erosionOtorhinolaryngologyRF1-547ENOtolaryngology Case Reports, Vol 21, Iss , Pp 100379- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Nasal-type NK/T-cell lymphoma Hidradenitis suppurativa Misdiagnosis Hard palate erosion Otorhinolaryngology RF1-547
spellingShingle	Nasal-type NK/T-cell lymphoma Hidradenitis suppurativa Misdiagnosis Hard palate erosion Otorhinolaryngology RF1-547 Clara M. Kerwin Anne E. Getz Nasal-type NK/T-cell lymphoma in a patient with hidradenitis suppurativa: A case report
description	Background: Nasal-type NK/T-cell lymphoma is a rare but deadly form of non-Hodgkin's lymphoma that initially presents with local symptoms including erythema, swelling, and epistaxis. Due to misdiagnosis and improper treatment with antibiotics, this tumor will frequently expand to involve nearby facial bones and the oropharynx, with characteristic erosion of the hard palate. Even with treatment, mortality rates are high. We present a case of Nasal-type NK/T-cell lymphoma in a patient whose disease was initially attributed to his pre-diagnosed hidradenitis suppurativa (HS). Case description: A 38-year old male presented with several weeks of progressive nasal swelling and redness, which he initially attributed to his pre-existing HS and self-treated with antibiotics. The patient was subsequently prescribed several courses of increasingly broad-spectrum antibiotics without improvement in his symptoms. Alternative non-infectious diagnoses were only given strong consideration once the tumor had grown to involve nearby structures including the maxilla, nasal sinuses, and oropharynx with characteristic erosion of the hard palate. Conclusions: Nasal-type NK/T-cell lymphoma is a rare and frequently misdiagnosed disease that can cause progressive morbidity and death if not properly treated. A broad differential should be maintained when evaluating prolonged nasal inflammation without systemic signs of infection, particularly when symptoms do not improve with antibiotic therapy.
format	article
author	Clara M. Kerwin Anne E. Getz
author_facet	Clara M. Kerwin Anne E. Getz
author_sort	Clara M. Kerwin
title	Nasal-type NK/T-cell lymphoma in a patient with hidradenitis suppurativa: A case report
title_short	Nasal-type NK/T-cell lymphoma in a patient with hidradenitis suppurativa: A case report
title_full	Nasal-type NK/T-cell lymphoma in a patient with hidradenitis suppurativa: A case report
title_fullStr	Nasal-type NK/T-cell lymphoma in a patient with hidradenitis suppurativa: A case report
title_full_unstemmed	Nasal-type NK/T-cell lymphoma in a patient with hidradenitis suppurativa: A case report
title_sort	nasal-type nk/t-cell lymphoma in a patient with hidradenitis suppurativa: a case report
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/207fa4f476b548cfbb22ff9f9f6cda35
work_keys_str_mv	AT claramkerwin nasaltypenktcelllymphomainapatientwithhidradenitissuppurativaacasereport AT anneegetz nasaltypenktcelllymphomainapatientwithhidradenitissuppurativaacasereport
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Nasal-type NK/T-cell lymphoma in a patient with hidradenitis suppurativa: A case report

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