High-throughput screening and rational design of biofunctionalized surfaces with optimized biocompatibility and antimicrobial activity

Optimizing the concentration of different functional peptides on a surface can be a complex process. Here, the authors report on the use of a click immobilization strategy to create gradients of two different functional peptides on a surface to screen different density functions for rapid optimizati...

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Autores principales: Zhou Fang, Junjian Chen, Ye Zhu, Guansong Hu, Haoqian Xin, Kunzhong Guo, Qingtao Li, Liangxu Xie, Lin Wang, Xuetao Shi, Yingjun Wang, Chuanbin Mao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/2083601208254d64a240abb7d269889c
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Sumario:Optimizing the concentration of different functional peptides on a surface can be a complex process. Here, the authors report on the use of a click immobilization strategy to create gradients of two different functional peptides on a surface to screen different density functions for rapid optimization.