High-throughput screening and rational design of biofunctionalized surfaces with optimized biocompatibility and antimicrobial activity

Optimizing the concentration of different functional peptides on a surface can be a complex process. Here, the authors report on the use of a click immobilization strategy to create gradients of two different functional peptides on a surface to screen different density functions for rapid optimizati...

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Autores principales:	Zhou Fang, Junjian Chen, Ye Zhu, Guansong Hu, Haoqian Xin, Kunzhong Guo, Qingtao Li, Liangxu Xie, Lin Wang, Xuetao Shi, Yingjun Wang, Chuanbin Mao
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2083601208254d64a240abb7d269889c
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spelling	oai:doaj.org-article:2083601208254d64a240abb7d269889c2021-12-02T17:40:33ZHigh-throughput screening and rational design of biofunctionalized surfaces with optimized biocompatibility and antimicrobial activity10.1038/s41467-021-23954-82041-1723https://doaj.org/article/2083601208254d64a240abb7d269889c2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23954-8https://doaj.org/toc/2041-1723Optimizing the concentration of different functional peptides on a surface can be a complex process. Here, the authors report on the use of a click immobilization strategy to create gradients of two different functional peptides on a surface to screen different density functions for rapid optimization.Zhou FangJunjian ChenYe ZhuGuansong HuHaoqian XinKunzhong GuoQingtao LiLiangxu XieLin WangXuetao ShiYingjun WangChuanbin MaoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Zhou Fang Junjian Chen Ye Zhu Guansong Hu Haoqian Xin Kunzhong Guo Qingtao Li Liangxu Xie Lin Wang Xuetao Shi Yingjun Wang Chuanbin Mao High-throughput screening and rational design of biofunctionalized surfaces with optimized biocompatibility and antimicrobial activity
description	Optimizing the concentration of different functional peptides on a surface can be a complex process. Here, the authors report on the use of a click immobilization strategy to create gradients of two different functional peptides on a surface to screen different density functions for rapid optimization.
format	article
author	Zhou Fang Junjian Chen Ye Zhu Guansong Hu Haoqian Xin Kunzhong Guo Qingtao Li Liangxu Xie Lin Wang Xuetao Shi Yingjun Wang Chuanbin Mao
author_facet	Zhou Fang Junjian Chen Ye Zhu Guansong Hu Haoqian Xin Kunzhong Guo Qingtao Li Liangxu Xie Lin Wang Xuetao Shi Yingjun Wang Chuanbin Mao
author_sort	Zhou Fang
title	High-throughput screening and rational design of biofunctionalized surfaces with optimized biocompatibility and antimicrobial activity
title_short	High-throughput screening and rational design of biofunctionalized surfaces with optimized biocompatibility and antimicrobial activity
title_full	High-throughput screening and rational design of biofunctionalized surfaces with optimized biocompatibility and antimicrobial activity
title_fullStr	High-throughput screening and rational design of biofunctionalized surfaces with optimized biocompatibility and antimicrobial activity
title_full_unstemmed	High-throughput screening and rational design of biofunctionalized surfaces with optimized biocompatibility and antimicrobial activity
title_sort	high-throughput screening and rational design of biofunctionalized surfaces with optimized biocompatibility and antimicrobial activity
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/2083601208254d64a240abb7d269889c
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High-throughput screening and rational design of biofunctionalized surfaces with optimized biocompatibility and antimicrobial activity

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