Comparison of micro-CT imaging and histology for approximal caries detection

Abstract Histological sectioning is a generally accepted in vitro validation method for caries detection techniques. However, it requires cumbersome sample preparation and induces irreversible sample destruction. Micro-Computer Tomography (micro-CT) allows non-destructive imaging of tooth structure....

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Autores principales:	C. Boca, B. Truyen, L. Henin, A. G. Schulte, V. Stachniss, N. De Clerck, J. Cornelis, P. Bottenberg
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/208f54cc98304d9f8e6d13a852876967
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spelling	oai:doaj.org-article:208f54cc98304d9f8e6d13a8528769672021-12-02T16:06:10ZComparison of micro-CT imaging and histology for approximal caries detection10.1038/s41598-017-06735-62045-2322https://doaj.org/article/208f54cc98304d9f8e6d13a8528769672017-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-06735-6https://doaj.org/toc/2045-2322Abstract Histological sectioning is a generally accepted in vitro validation method for caries detection techniques. However, it requires cumbersome sample preparation and induces irreversible sample destruction. Micro-Computer Tomography (micro-CT) allows non-destructive imaging of tooth structure. The aim of this study was to compare the performance of histological sectioning and micro-CT imaging in detecting approximal carious lesions. Unlike previous studies, evaluation is objectified by comparing visual appearance of exactly corresponding anatomical regions. Sixty extracted human teeth were scanned with a desktop micro CT system. Axial histological slices were prepared and photographed. Sample preparation, combined with dedicated image processing, ensured selection of identical anatomical regions on radiographic and histological images. Evaluation of the presence and extent of carious lesions was performed by four dentists using custom-designed software. Each section was scored independently (histo or micro CT). Scores of approximal surfaces were retained for further analysis. Spearman’s correlation coefficients (0.738 to 0.829, p < 0.0001) showed a good agreement between signs of carious lesions in the identical region obtained with both methods. Bland-Altman plots showed that 90.76% of the data points were within the limits of agreement. Micro-CT imaging was shown to provide an interesting alternative to histological sectioning as detection method for carious lesions.C. BocaB. TruyenL. HeninA. G. SchulteV. StachnissN. De ClerckJ. CornelisP. BottenbergNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q C. Boca B. Truyen L. Henin A. G. Schulte V. Stachniss N. De Clerck J. Cornelis P. Bottenberg Comparison of micro-CT imaging and histology for approximal caries detection
description	Abstract Histological sectioning is a generally accepted in vitro validation method for caries detection techniques. However, it requires cumbersome sample preparation and induces irreversible sample destruction. Micro-Computer Tomography (micro-CT) allows non-destructive imaging of tooth structure. The aim of this study was to compare the performance of histological sectioning and micro-CT imaging in detecting approximal carious lesions. Unlike previous studies, evaluation is objectified by comparing visual appearance of exactly corresponding anatomical regions. Sixty extracted human teeth were scanned with a desktop micro CT system. Axial histological slices were prepared and photographed. Sample preparation, combined with dedicated image processing, ensured selection of identical anatomical regions on radiographic and histological images. Evaluation of the presence and extent of carious lesions was performed by four dentists using custom-designed software. Each section was scored independently (histo or micro CT). Scores of approximal surfaces were retained for further analysis. Spearman’s correlation coefficients (0.738 to 0.829, p < 0.0001) showed a good agreement between signs of carious lesions in the identical region obtained with both methods. Bland-Altman plots showed that 90.76% of the data points were within the limits of agreement. Micro-CT imaging was shown to provide an interesting alternative to histological sectioning as detection method for carious lesions.
format	article
author	C. Boca B. Truyen L. Henin A. G. Schulte V. Stachniss N. De Clerck J. Cornelis P. Bottenberg
author_facet	C. Boca B. Truyen L. Henin A. G. Schulte V. Stachniss N. De Clerck J. Cornelis P. Bottenberg
author_sort	C. Boca
title	Comparison of micro-CT imaging and histology for approximal caries detection
title_short	Comparison of micro-CT imaging and histology for approximal caries detection
title_full	Comparison of micro-CT imaging and histology for approximal caries detection
title_fullStr	Comparison of micro-CT imaging and histology for approximal caries detection
title_full_unstemmed	Comparison of micro-CT imaging and histology for approximal caries detection
title_sort	comparison of micro-ct imaging and histology for approximal caries detection
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/208f54cc98304d9f8e6d13a852876967
work_keys_str_mv	AT cboca comparisonofmicroctimagingandhistologyforapproximalcariesdetection AT btruyen comparisonofmicroctimagingandhistologyforapproximalcariesdetection AT lhenin comparisonofmicroctimagingandhistologyforapproximalcariesdetection AT agschulte comparisonofmicroctimagingandhistologyforapproximalcariesdetection AT vstachniss comparisonofmicroctimagingandhistologyforapproximalcariesdetection AT ndeclerck comparisonofmicroctimagingandhistologyforapproximalcariesdetection AT jcornelis comparisonofmicroctimagingandhistologyforapproximalcariesdetection AT pbottenberg comparisonofmicroctimagingandhistologyforapproximalcariesdetection
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Comparison of micro-CT imaging and histology for approximal caries detection

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