Intravitreal triamcinolone for intraocular inflammation and associated macular edema

Steven M Couch, Sophie J BakriMayo Clinic Department of Ophthalmology, Mayo Clinic, Rochester, MN, USAAbstract: Triamcinolone acetonide (TA) is a corticosteroid that has many uses in the treatment of ocular diseases because of its potent anti-inflammatory and anti-permeability actions. Intraocular i...

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Autores principales: Steven M Couch, Sophie J Bakri
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Publicado: Dove Medical Press 2008
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Acceso en línea:https://doaj.org/article/2099e6f709e24774ad57cc5b2f531d2a
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spelling oai:doaj.org-article:2099e6f709e24774ad57cc5b2f531d2a2021-12-02T00:51:11ZIntravitreal triamcinolone for intraocular inflammation and associated macular edema1177-54671177-5483https://doaj.org/article/2099e6f709e24774ad57cc5b2f531d2a2008-11-01T00:00:00Zhttp://www.dovepress.com/intravitreal-triamcinolone-for-intraocular-inflammation-and-associated-a2529https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Steven M Couch, Sophie J BakriMayo Clinic Department of Ophthalmology, Mayo Clinic, Rochester, MN, USAAbstract: Triamcinolone acetonide (TA) is a corticosteroid that has many uses in the treatment of ocular diseases because of its potent anti-inflammatory and anti-permeability actions. Intraocular inflammation broadly referred to as uveitis can result from several causes, including the immune system and after ophthalmic surgery. One of the most common reasons for vision loss with uveitis is macular edema. TA has been used for many years as an intravitreal injection for the treatment of ocular diseases. Several case control studies have been reported showing the efficacy of TA in the treatment of intraocular inflammation and associated macular edema caused by Behcet’s disease, Vogt-Koyanagi-Harada syndrome, sympathetic ophthalmia and white dot syndromes. It has also been shown efficacious in cases of pars planitis and idiopathic posterior uveitis. Some authors have reported its use in postoperative cystoid macular edema. Many of the studies on the use of TA in controlling intraocular inflammation and concomitant macular edema showed its effect to be transient in many patients requiring reinjection. Complications can arise from intravitreal injection of TA including elevated intraocular pressure and cataract. Rarely, it can be associated with infectious and non-infectious endophthalmitis. TA may be useful as an adjuvant in the treatment of uveitis and its associated macular edema, especially in patients resistant or intolerant to standard treatment.Keywords: triamcinolone acetonide, Behcet’s disease, sympathetic ophthalmia, Vogt-Koyanagi-Harada syndrome, white dot syndromes, uveitis, cataract surgery, macular edema, endophthalmitis Steven M CouchSophie J BakriDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2009, Iss default, Pp 41-47 (2008)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Steven M Couch
Sophie J Bakri
Intravitreal triamcinolone for intraocular inflammation and associated macular edema
description Steven M Couch, Sophie J BakriMayo Clinic Department of Ophthalmology, Mayo Clinic, Rochester, MN, USAAbstract: Triamcinolone acetonide (TA) is a corticosteroid that has many uses in the treatment of ocular diseases because of its potent anti-inflammatory and anti-permeability actions. Intraocular inflammation broadly referred to as uveitis can result from several causes, including the immune system and after ophthalmic surgery. One of the most common reasons for vision loss with uveitis is macular edema. TA has been used for many years as an intravitreal injection for the treatment of ocular diseases. Several case control studies have been reported showing the efficacy of TA in the treatment of intraocular inflammation and associated macular edema caused by Behcet’s disease, Vogt-Koyanagi-Harada syndrome, sympathetic ophthalmia and white dot syndromes. It has also been shown efficacious in cases of pars planitis and idiopathic posterior uveitis. Some authors have reported its use in postoperative cystoid macular edema. Many of the studies on the use of TA in controlling intraocular inflammation and concomitant macular edema showed its effect to be transient in many patients requiring reinjection. Complications can arise from intravitreal injection of TA including elevated intraocular pressure and cataract. Rarely, it can be associated with infectious and non-infectious endophthalmitis. TA may be useful as an adjuvant in the treatment of uveitis and its associated macular edema, especially in patients resistant or intolerant to standard treatment.Keywords: triamcinolone acetonide, Behcet’s disease, sympathetic ophthalmia, Vogt-Koyanagi-Harada syndrome, white dot syndromes, uveitis, cataract surgery, macular edema, endophthalmitis
format article
author Steven M Couch
Sophie J Bakri
author_facet Steven M Couch
Sophie J Bakri
author_sort Steven M Couch
title Intravitreal triamcinolone for intraocular inflammation and associated macular edema
title_short Intravitreal triamcinolone for intraocular inflammation and associated macular edema
title_full Intravitreal triamcinolone for intraocular inflammation and associated macular edema
title_fullStr Intravitreal triamcinolone for intraocular inflammation and associated macular edema
title_full_unstemmed Intravitreal triamcinolone for intraocular inflammation and associated macular edema
title_sort intravitreal triamcinolone for intraocular inflammation and associated macular edema
publisher Dove Medical Press
publishDate 2008
url https://doaj.org/article/2099e6f709e24774ad57cc5b2f531d2a
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AT sophiejbakri intravitrealtriamcinoloneforintraocularinflammationandassociatedmacularedema
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