Stabilin receptors clear LPS and control systemic inflammation

Stabilin receptors clear LPS and control systemic inflammation

Summary: Lipopolysaccharides (LPSs) cause lethal endotoxemia if not rapidly cleared from blood circulation. Liver sinusoidal endothelial cells (LSEC) systemically clear LPS by unknown mechanisms. We discovered that LPS clearance through LSEC involves endocytosis and lysosomal inactivation via Stabil...

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Detalles Bibliográficos
Autores principales: Fatima Cabral, Mustafa Al-Rahem, John Skaggs, Thushara A. Thomas, Naresh Kumar, Qian Wu, Paolo Fadda, Lianbo Yu, John M. Robinson, Jonghan Kim, Ekta Pandey, Xinghui Sun, Wael N. Jarjour, Murugesan V.S. Rajaram, Edward N. Harris, Latha P. Ganesan
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
Materias:
Biological sciences
Molecular biology
Immune response
Science
Q
Acceso en línea:https://doaj.org/article/209b703b99394a00aadccb8cd283ebee
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