The role of the e3 ligase cbl-B in murine dendritic cells.

The role of the e3 ligase cbl-B in murine dendritic cells.

Dendritic cells (DCs) are potent antigen-presenting cells with a promising potential in cancer immunotherapy. Cbl proteins are E3 ubiquitin ligases and have been implicated in regulating the functional activity of various immune cells. As an example, c-Cbl negatively affects DC activation. We here d...

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Autores principales: Stephanie Wallner, Christina Lutz-Nicoladoni, Christoph H Tripp, Günther Gastl, Gottfried Baier, Josef M Penninger, Patrizia Stoitzner, Dominik Wolf
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/209bcfc1e9cd438e883ad9a9efb60cfd
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