ANTIBODIES TO LEUKEMIA DIFFERENTIATION FACTOR (HLDF) IN PATIENTS WITH GASTROINTESTINAL CANCER
Antibodies to leukemia differentiation factor (HLDF) in patients with gastrointestinal cancer Abstract. Patients with gastric cancer exhibit higher levels of IgG4-antibodies to human leukemia differentiation factor (HLDF), as compared with healthy individuals, whereas, in patients with colorectal ca...
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oai:doaj.org-article:209c7f85a6db4c8a8c11135ce24f6dc02021-11-18T08:03:37ZANTIBODIES TO LEUKEMIA DIFFERENTIATION FACTOR (HLDF) IN PATIENTS WITH GASTROINTESTINAL CANCER1563-06252313-741X10.15789/1563-0625-2010-1-2-49-56https://doaj.org/article/209c7f85a6db4c8a8c11135ce24f6dc02014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/41https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAntibodies to leukemia differentiation factor (HLDF) in patients with gastrointestinal cancer Abstract. Patients with gastric cancer exhibit higher levels of IgG4-antibodies to human leukemia differentiation factor (HLDF), as compared with healthy individuals, whereas, in patients with colorectal cancer, one may detect high levels of IgA anti-HDLF antibodies, along with lower levels of IgG1 class antibodies against HLDF than in control group. Among patients with gastrointestinal cancer, a positive correlation is revealed between contents of highly differentiated cells in the tumor, and IgM antibodies to HDLF. Meanwhile, a reverse relationship is noted between low differentiation of tumor cells and levels of IgG2 antibodies to HDLF in gastric cancer patients, or IgG3 antibodies to HDLF in patients with colorectal cancer.A. I. AutenshlusA. V. SosninaE. S. MikhailivaA. P. LykovYu. V. TumanovE. D. DanilankoV. S. SamukovI. A. KostanyanD. V. MorozovM. M. CherenkovaL. .A. ThvanN. A. VaraksinSPb RAACIarticlehdlfautoantibodiescytokinesgastrointestinal cancerImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 12, Iss 1-2, Pp 49-56 (2014) |
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hdlf autoantibodies cytokines gastrointestinal cancer Immunologic diseases. Allergy RC581-607 |
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hdlf autoantibodies cytokines gastrointestinal cancer Immunologic diseases. Allergy RC581-607 A. I. Autenshlus A. V. Sosnina E. S. Mikhailiva A. P. Lykov Yu. V. Tumanov E. D. Danilanko V. S. Samukov I. A. Kostanyan D. V. Morozov M. M. Cherenkova L. .A. Thvan N. A. Varaksin ANTIBODIES TO LEUKEMIA DIFFERENTIATION FACTOR (HLDF) IN PATIENTS WITH GASTROINTESTINAL CANCER |
description |
Antibodies to leukemia differentiation factor (HLDF) in patients with gastrointestinal cancer Abstract. Patients with gastric cancer exhibit higher levels of IgG4-antibodies to human leukemia differentiation factor (HLDF), as compared with healthy individuals, whereas, in patients with colorectal cancer, one may detect high levels of IgA anti-HDLF antibodies, along with lower levels of IgG1 class antibodies against HLDF than in control group. Among patients with gastrointestinal cancer, a positive correlation is revealed between contents of highly differentiated cells in the tumor, and IgM antibodies to HDLF. Meanwhile, a reverse relationship is noted between low differentiation of tumor cells and levels of IgG2 antibodies to HDLF in gastric cancer patients, or IgG3 antibodies to HDLF in patients with colorectal cancer. |
format |
article |
author |
A. I. Autenshlus A. V. Sosnina E. S. Mikhailiva A. P. Lykov Yu. V. Tumanov E. D. Danilanko V. S. Samukov I. A. Kostanyan D. V. Morozov M. M. Cherenkova L. .A. Thvan N. A. Varaksin |
author_facet |
A. I. Autenshlus A. V. Sosnina E. S. Mikhailiva A. P. Lykov Yu. V. Tumanov E. D. Danilanko V. S. Samukov I. A. Kostanyan D. V. Morozov M. M. Cherenkova L. .A. Thvan N. A. Varaksin |
author_sort |
A. I. Autenshlus |
title |
ANTIBODIES TO LEUKEMIA DIFFERENTIATION FACTOR (HLDF) IN PATIENTS WITH GASTROINTESTINAL CANCER |
title_short |
ANTIBODIES TO LEUKEMIA DIFFERENTIATION FACTOR (HLDF) IN PATIENTS WITH GASTROINTESTINAL CANCER |
title_full |
ANTIBODIES TO LEUKEMIA DIFFERENTIATION FACTOR (HLDF) IN PATIENTS WITH GASTROINTESTINAL CANCER |
title_fullStr |
ANTIBODIES TO LEUKEMIA DIFFERENTIATION FACTOR (HLDF) IN PATIENTS WITH GASTROINTESTINAL CANCER |
title_full_unstemmed |
ANTIBODIES TO LEUKEMIA DIFFERENTIATION FACTOR (HLDF) IN PATIENTS WITH GASTROINTESTINAL CANCER |
title_sort |
antibodies to leukemia differentiation factor (hldf) in patients with gastrointestinal cancer |
publisher |
SPb RAACI |
publishDate |
2014 |
url |
https://doaj.org/article/209c7f85a6db4c8a8c11135ce24f6dc0 |
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