ANTIBODIES TO LEUKEMIA DIFFERENTIATION FACTOR (HLDF) IN PATIENTS WITH GASTROINTESTINAL CANCER

Antibodies to leukemia differentiation factor (HLDF) in patients with gastrointestinal cancer Abstract. Patients with gastric cancer exhibit higher levels of IgG4-antibodies to human leukemia differentiation factor (HLDF), as compared with healthy individuals, whereas, in patients with colorectal ca...

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Autores principales: A. I. Autenshlus, A. V. Sosnina, E. S. Mikhailiva, A. P. Lykov, Yu. V. Tumanov, E. D. Danilanko, V. S. Samukov, I. A. Kostanyan, D. V. Morozov, M. M. Cherenkova, L. .A. Thvan, N. A. Varaksin
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Lenguaje:RU
Publicado: SPb RAACI 2014
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Acceso en línea:https://doaj.org/article/209c7f85a6db4c8a8c11135ce24f6dc0
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spelling oai:doaj.org-article:209c7f85a6db4c8a8c11135ce24f6dc02021-11-18T08:03:37ZANTIBODIES TO LEUKEMIA DIFFERENTIATION FACTOR (HLDF) IN PATIENTS WITH GASTROINTESTINAL CANCER1563-06252313-741X10.15789/1563-0625-2010-1-2-49-56https://doaj.org/article/209c7f85a6db4c8a8c11135ce24f6dc02014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/41https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAntibodies to leukemia differentiation factor (HLDF) in patients with gastrointestinal cancer Abstract. Patients with gastric cancer exhibit higher levels of IgG4-antibodies to human leukemia differentiation factor (HLDF), as compared with healthy individuals, whereas, in patients with colorectal cancer, one may detect high levels of IgA anti-HDLF antibodies, along with lower levels of IgG1 class antibodies against HLDF than in control group. Among patients with gastrointestinal cancer, a positive correlation is revealed between contents of highly differentiated cells in the tumor, and IgM antibodies to HDLF. Meanwhile, a reverse relationship is noted between low differentiation of tumor cells and levels of IgG2 antibodies to HDLF in gastric cancer patients, or IgG3 antibodies to HDLF in patients with colorectal cancer.A. I. AutenshlusA. V. SosninaE. S. MikhailivaA. P. LykovYu. V. TumanovE. D. DanilankoV. S. SamukovI. A. KostanyanD. V. MorozovM. M. CherenkovaL. .A. ThvanN. A. VaraksinSPb RAACIarticlehdlfautoantibodiescytokinesgastrointestinal cancerImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 12, Iss 1-2, Pp 49-56 (2014)
institution DOAJ
collection DOAJ
language RU
topic hdlf
autoantibodies
cytokines
gastrointestinal cancer
Immunologic diseases. Allergy
RC581-607
spellingShingle hdlf
autoantibodies
cytokines
gastrointestinal cancer
Immunologic diseases. Allergy
RC581-607
A. I. Autenshlus
A. V. Sosnina
E. S. Mikhailiva
A. P. Lykov
Yu. V. Tumanov
E. D. Danilanko
V. S. Samukov
I. A. Kostanyan
D. V. Morozov
M. M. Cherenkova
L. .A. Thvan
N. A. Varaksin
ANTIBODIES TO LEUKEMIA DIFFERENTIATION FACTOR (HLDF) IN PATIENTS WITH GASTROINTESTINAL CANCER
description Antibodies to leukemia differentiation factor (HLDF) in patients with gastrointestinal cancer Abstract. Patients with gastric cancer exhibit higher levels of IgG4-antibodies to human leukemia differentiation factor (HLDF), as compared with healthy individuals, whereas, in patients with colorectal cancer, one may detect high levels of IgA anti-HDLF antibodies, along with lower levels of IgG1 class antibodies against HLDF than in control group. Among patients with gastrointestinal cancer, a positive correlation is revealed between contents of highly differentiated cells in the tumor, and IgM antibodies to HDLF. Meanwhile, a reverse relationship is noted between low differentiation of tumor cells and levels of IgG2 antibodies to HDLF in gastric cancer patients, or IgG3 antibodies to HDLF in patients with colorectal cancer.
format article
author A. I. Autenshlus
A. V. Sosnina
E. S. Mikhailiva
A. P. Lykov
Yu. V. Tumanov
E. D. Danilanko
V. S. Samukov
I. A. Kostanyan
D. V. Morozov
M. M. Cherenkova
L. .A. Thvan
N. A. Varaksin
author_facet A. I. Autenshlus
A. V. Sosnina
E. S. Mikhailiva
A. P. Lykov
Yu. V. Tumanov
E. D. Danilanko
V. S. Samukov
I. A. Kostanyan
D. V. Morozov
M. M. Cherenkova
L. .A. Thvan
N. A. Varaksin
author_sort A. I. Autenshlus
title ANTIBODIES TO LEUKEMIA DIFFERENTIATION FACTOR (HLDF) IN PATIENTS WITH GASTROINTESTINAL CANCER
title_short ANTIBODIES TO LEUKEMIA DIFFERENTIATION FACTOR (HLDF) IN PATIENTS WITH GASTROINTESTINAL CANCER
title_full ANTIBODIES TO LEUKEMIA DIFFERENTIATION FACTOR (HLDF) IN PATIENTS WITH GASTROINTESTINAL CANCER
title_fullStr ANTIBODIES TO LEUKEMIA DIFFERENTIATION FACTOR (HLDF) IN PATIENTS WITH GASTROINTESTINAL CANCER
title_full_unstemmed ANTIBODIES TO LEUKEMIA DIFFERENTIATION FACTOR (HLDF) IN PATIENTS WITH GASTROINTESTINAL CANCER
title_sort antibodies to leukemia differentiation factor (hldf) in patients with gastrointestinal cancer
publisher SPb RAACI
publishDate 2014
url https://doaj.org/article/209c7f85a6db4c8a8c11135ce24f6dc0
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