Change of Levels of NGF, ACTH, and AVP in the Cerebrospinal Fluid after Decompressive Craniectomy of Craniocerebral Injury and Their Relationship with Communicating Hydrocephalus

In recent years, the incidence of craniocerebral trauma has increased, making it one of the important causes of death and disability in neurosurgery patients. The decompressive craniectomy (DC) after severe craniocerebral injury has become the preferred treatment for patients with severe craniocereb...

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Autores principales:	Liang Wang, Shuangbo Fan, Zhenping Zhao, Qian Xu
Formato:	article
Lenguaje:	EN
Publicado:	Hindawi Limited 2021
Materias:	Other systems of medicine RZ201-999
Acceso en línea:	https://doaj.org/article/20a8da1edffb4eccb79ae178b38d02bb
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spelling	oai:doaj.org-article:20a8da1edffb4eccb79ae178b38d02bb2021-11-08T02:36:18ZChange of Levels of NGF, ACTH, and AVP in the Cerebrospinal Fluid after Decompressive Craniectomy of Craniocerebral Injury and Their Relationship with Communicating Hydrocephalus1741-428810.1155/2021/1519904https://doaj.org/article/20a8da1edffb4eccb79ae178b38d02bb2021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/1519904https://doaj.org/toc/1741-4288In recent years, the incidence of craniocerebral trauma has increased, making it one of the important causes of death and disability in neurosurgery patients. The decompressive craniectomy (DC) after severe craniocerebral injury has become the preferred treatment for patients with severe craniocerebral injury, but the incidence of postoperative hydrocephalus has become a difficult problem in clinical treatment. This study observed the changes of nerve growth factor (NGF), adrenocorticotropic hormone (ACTH), and arginine vasopressin (AVP) levels in the CSF after DC in patients with craniocerebral injury and analyzed the relationship between the three indicators and communicating hydrocephalus. The results showed that the levels of NGF, ACTH, and AVP in patients with cranial injury after DC were significantly higher than those in healthy subjects, and subdural effusion, traumatic subarachnoid hemorrhage (tSAH), and the levels of NGF, ACTH, and AVP in the CSF were independent risk factors for communicating hydrocephalus. Monitoring the levels of NGF, ACTH, and AVP is of great significance for clinicians to judge the occurrence of traffic hydrocephalus, evaluate the prognosis of patients with craniocerebral injury after DC, and guide clinical treatment.Liang WangShuangbo FanZhenping ZhaoQian XuHindawi LimitedarticleOther systems of medicineRZ201-999ENEvidence-Based Complementary and Alternative Medicine, Vol 2021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Other systems of medicine RZ201-999
spellingShingle	Other systems of medicine RZ201-999 Liang Wang Shuangbo Fan Zhenping Zhao Qian Xu Change of Levels of NGF, ACTH, and AVP in the Cerebrospinal Fluid after Decompressive Craniectomy of Craniocerebral Injury and Their Relationship with Communicating Hydrocephalus
description	In recent years, the incidence of craniocerebral trauma has increased, making it one of the important causes of death and disability in neurosurgery patients. The decompressive craniectomy (DC) after severe craniocerebral injury has become the preferred treatment for patients with severe craniocerebral injury, but the incidence of postoperative hydrocephalus has become a difficult problem in clinical treatment. This study observed the changes of nerve growth factor (NGF), adrenocorticotropic hormone (ACTH), and arginine vasopressin (AVP) levels in the CSF after DC in patients with craniocerebral injury and analyzed the relationship between the three indicators and communicating hydrocephalus. The results showed that the levels of NGF, ACTH, and AVP in patients with cranial injury after DC were significantly higher than those in healthy subjects, and subdural effusion, traumatic subarachnoid hemorrhage (tSAH), and the levels of NGF, ACTH, and AVP in the CSF were independent risk factors for communicating hydrocephalus. Monitoring the levels of NGF, ACTH, and AVP is of great significance for clinicians to judge the occurrence of traffic hydrocephalus, evaluate the prognosis of patients with craniocerebral injury after DC, and guide clinical treatment.
format	article
author	Liang Wang Shuangbo Fan Zhenping Zhao Qian Xu
author_facet	Liang Wang Shuangbo Fan Zhenping Zhao Qian Xu
author_sort	Liang Wang
title	Change of Levels of NGF, ACTH, and AVP in the Cerebrospinal Fluid after Decompressive Craniectomy of Craniocerebral Injury and Their Relationship with Communicating Hydrocephalus
title_short	Change of Levels of NGF, ACTH, and AVP in the Cerebrospinal Fluid after Decompressive Craniectomy of Craniocerebral Injury and Their Relationship with Communicating Hydrocephalus
title_full	Change of Levels of NGF, ACTH, and AVP in the Cerebrospinal Fluid after Decompressive Craniectomy of Craniocerebral Injury and Their Relationship with Communicating Hydrocephalus
title_fullStr	Change of Levels of NGF, ACTH, and AVP in the Cerebrospinal Fluid after Decompressive Craniectomy of Craniocerebral Injury and Their Relationship with Communicating Hydrocephalus
title_full_unstemmed	Change of Levels of NGF, ACTH, and AVP in the Cerebrospinal Fluid after Decompressive Craniectomy of Craniocerebral Injury and Their Relationship with Communicating Hydrocephalus
title_sort	change of levels of ngf, acth, and avp in the cerebrospinal fluid after decompressive craniectomy of craniocerebral injury and their relationship with communicating hydrocephalus
publisher	Hindawi Limited
publishDate	2021
url	https://doaj.org/article/20a8da1edffb4eccb79ae178b38d02bb
work_keys_str_mv	AT liangwang changeoflevelsofngfacthandavpinthecerebrospinalfluidafterdecompressivecraniectomyofcraniocerebralinjuryandtheirrelationshipwithcommunicatinghydrocephalus AT shuangbofan changeoflevelsofngfacthandavpinthecerebrospinalfluidafterdecompressivecraniectomyofcraniocerebralinjuryandtheirrelationshipwithcommunicatinghydrocephalus AT zhenpingzhao changeoflevelsofngfacthandavpinthecerebrospinalfluidafterdecompressivecraniectomyofcraniocerebralinjuryandtheirrelationshipwithcommunicatinghydrocephalus AT qianxu changeoflevelsofngfacthandavpinthecerebrospinalfluidafterdecompressivecraniectomyofcraniocerebralinjuryandtheirrelationshipwithcommunicatinghydrocephalus
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Change of Levels of NGF, ACTH, and AVP in the Cerebrospinal Fluid after Decompressive Craniectomy of Craniocerebral Injury and Their Relationship with Communicating Hydrocephalus

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