Investigation of intraocular pressure of the anterior chamber and vitreous cavity of porcine eyes via a novel method

Abstract To evaluate a new method of measuring the intraocular pressure (IOP) in the vitreous cavity. IOPs in the anterior chamber and vitreous cavities of 24 porcine eyes (12 eyes with lenses and 12 eyes without lenses) were measured directly, continuously, and simultaneously. We used a needle as a...

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Autores principales:	Koji Nagae, Hiromasa Sawamura, Makoto Aihara
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/20adc49e048749bf8af255c16561ee49
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spelling	oai:doaj.org-article:20adc49e048749bf8af255c16561ee492021-12-02T16:08:37ZInvestigation of intraocular pressure of the anterior chamber and vitreous cavity of porcine eyes via a novel method10.1038/s41598-020-77633-72045-2322https://doaj.org/article/20adc49e048749bf8af255c16561ee492020-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-77633-7https://doaj.org/toc/2045-2322Abstract To evaluate a new method of measuring the intraocular pressure (IOP) in the vitreous cavity. IOPs in the anterior chamber and vitreous cavities of 24 porcine eyes (12 eyes with lenses and 12 eyes without lenses) were measured directly, continuously, and simultaneously. We used a needle as a part of the pressure sensor to measure the anterior chamber IOP and a disk-shaped sensor to measure the vitreous cavity IOP. A significant group-by-condition interaction on the vitreous cavity IOP between the two groups (phakia and aphakia) and four conditions of anterior chamber IOP were observed (F[3,258] = 5.8564, p < 0.001). A positive correlation was observed between the vitreous cavity IOP and anterior chamber IOP in both the phakia group (R = 0.96, p < 0.001) and the aphakia group (R = 0.97, p < 0.001). No significant correlation was observed between the ΔIOPv-a (vitreous cavity IOP − anterior chamber IOP) and anterior chamber IOP in either group (phakia group: R = − 0.18, p = 0.034; aphakia group: R = − 0.029, p = 0.73). The vitreous cavity IOP measured with the new sensor was well-correlated with the anterior chamber IOP in the physiological range tested.Koji NagaeHiromasa SawamuraMakoto AiharaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 10, Iss 1, Pp 1-6 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Koji Nagae Hiromasa Sawamura Makoto Aihara Investigation of intraocular pressure of the anterior chamber and vitreous cavity of porcine eyes via a novel method
description	Abstract To evaluate a new method of measuring the intraocular pressure (IOP) in the vitreous cavity. IOPs in the anterior chamber and vitreous cavities of 24 porcine eyes (12 eyes with lenses and 12 eyes without lenses) were measured directly, continuously, and simultaneously. We used a needle as a part of the pressure sensor to measure the anterior chamber IOP and a disk-shaped sensor to measure the vitreous cavity IOP. A significant group-by-condition interaction on the vitreous cavity IOP between the two groups (phakia and aphakia) and four conditions of anterior chamber IOP were observed (F[3,258] = 5.8564, p < 0.001). A positive correlation was observed between the vitreous cavity IOP and anterior chamber IOP in both the phakia group (R = 0.96, p < 0.001) and the aphakia group (R = 0.97, p < 0.001). No significant correlation was observed between the ΔIOPv-a (vitreous cavity IOP − anterior chamber IOP) and anterior chamber IOP in either group (phakia group: R = − 0.18, p = 0.034; aphakia group: R = − 0.029, p = 0.73). The vitreous cavity IOP measured with the new sensor was well-correlated with the anterior chamber IOP in the physiological range tested.
format	article
author	Koji Nagae Hiromasa Sawamura Makoto Aihara
author_facet	Koji Nagae Hiromasa Sawamura Makoto Aihara
author_sort	Koji Nagae
title	Investigation of intraocular pressure of the anterior chamber and vitreous cavity of porcine eyes via a novel method
title_short	Investigation of intraocular pressure of the anterior chamber and vitreous cavity of porcine eyes via a novel method
title_full	Investigation of intraocular pressure of the anterior chamber and vitreous cavity of porcine eyes via a novel method
title_fullStr	Investigation of intraocular pressure of the anterior chamber and vitreous cavity of porcine eyes via a novel method
title_full_unstemmed	Investigation of intraocular pressure of the anterior chamber and vitreous cavity of porcine eyes via a novel method
title_sort	investigation of intraocular pressure of the anterior chamber and vitreous cavity of porcine eyes via a novel method
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/20adc49e048749bf8af255c16561ee49
work_keys_str_mv	AT kojinagae investigationofintraocularpressureoftheanteriorchamberandvitreouscavityofporcineeyesviaanovelmethod AT hiromasasawamura investigationofintraocularpressureoftheanteriorchamberandvitreouscavityofporcineeyesviaanovelmethod AT makotoaihara investigationofintraocularpressureoftheanteriorchamberandvitreouscavityofporcineeyesviaanovelmethod
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Investigation of intraocular pressure of the anterior chamber and vitreous cavity of porcine eyes via a novel method

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