A role for programmed cell death in the microbial loop.

The microbial loop is the conventional model by which nutrients and minerals are recycled in aquatic eco-systems. Biochemical pathways in different organisms become metabolically inter-connected such that nutrients are utilized, processed, released and re-utilized by others. The result is that unrel...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Mónica V Orellana, Wyming L Pang, Pierre M Durand, Kenia Whitehead, Nitin S Baliga
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/20b4d952847c4733b6389ec7e5b8db4a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:20b4d952847c4733b6389ec7e5b8db4a
record_format	dspace
spelling	oai:doaj.org-article:20b4d952847c4733b6389ec7e5b8db4a2021-11-18T07:46:22ZA role for programmed cell death in the microbial loop.1932-620310.1371/journal.pone.0062595https://doaj.org/article/20b4d952847c4733b6389ec7e5b8db4a2013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23667496/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203The microbial loop is the conventional model by which nutrients and minerals are recycled in aquatic eco-systems. Biochemical pathways in different organisms become metabolically inter-connected such that nutrients are utilized, processed, released and re-utilized by others. The result is that unrelated individuals end up impacting each others' fitness directly through their metabolic activities. This study focused on the impact of programmed cell death (PCD) on a population's growth as well as its role in the exchange of carbon between two naturally co-occurring halophilic organisms. Flow cytometric, biochemical, ¹⁴C radioisotope tracing assays, and global transcriptomic analyses show that organic algal photosynthate released by Dunalliela salina cells undergoing PCD complements the nutritional needs of other non-PCD D. salina cells. This occurs in vitro in a carbon limited environment and enhances the growth of the population. In addition, a co-occurring heterotroph Halobacterium salinarum re-mineralizes the carbon providing elemental nutrients for the mixoheterotrophic chlorophyte. The significance of this is uncertain and the archaeon can also subsist entirely on the lysate of apoptotic algae. PCD is now well established in unicellular organisms; however its ecological relevance has been difficult to decipher. In this study we found that PCD in D. salina causes the release of organic nutrients such as glycerol, which can be used by others in the population as well as a co-occurring halophilic archaeon. H. salinarum also re-mineralizes the dissolved material promoting algal growth. PCD in D. salina was the mechanism for the flow of dissolved photosynthate between unrelated organisms. Ironically, programmed death plays a central role in an organism's own population growth and in the exchange of nutrients in the microbial loop.Mónica V OrellanaWyming L PangPierre M DurandKenia WhiteheadNitin S BaligaPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 5, p e62595 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Mónica V Orellana Wyming L Pang Pierre M Durand Kenia Whitehead Nitin S Baliga A role for programmed cell death in the microbial loop.
description	The microbial loop is the conventional model by which nutrients and minerals are recycled in aquatic eco-systems. Biochemical pathways in different organisms become metabolically inter-connected such that nutrients are utilized, processed, released and re-utilized by others. The result is that unrelated individuals end up impacting each others' fitness directly through their metabolic activities. This study focused on the impact of programmed cell death (PCD) on a population's growth as well as its role in the exchange of carbon between two naturally co-occurring halophilic organisms. Flow cytometric, biochemical, ¹⁴C radioisotope tracing assays, and global transcriptomic analyses show that organic algal photosynthate released by Dunalliela salina cells undergoing PCD complements the nutritional needs of other non-PCD D. salina cells. This occurs in vitro in a carbon limited environment and enhances the growth of the population. In addition, a co-occurring heterotroph Halobacterium salinarum re-mineralizes the carbon providing elemental nutrients for the mixoheterotrophic chlorophyte. The significance of this is uncertain and the archaeon can also subsist entirely on the lysate of apoptotic algae. PCD is now well established in unicellular organisms; however its ecological relevance has been difficult to decipher. In this study we found that PCD in D. salina causes the release of organic nutrients such as glycerol, which can be used by others in the population as well as a co-occurring halophilic archaeon. H. salinarum also re-mineralizes the dissolved material promoting algal growth. PCD in D. salina was the mechanism for the flow of dissolved photosynthate between unrelated organisms. Ironically, programmed death plays a central role in an organism's own population growth and in the exchange of nutrients in the microbial loop.
format	article
author	Mónica V Orellana Wyming L Pang Pierre M Durand Kenia Whitehead Nitin S Baliga
author_facet	Mónica V Orellana Wyming L Pang Pierre M Durand Kenia Whitehead Nitin S Baliga
author_sort	Mónica V Orellana
title	A role for programmed cell death in the microbial loop.
title_short	A role for programmed cell death in the microbial loop.
title_full	A role for programmed cell death in the microbial loop.
title_fullStr	A role for programmed cell death in the microbial loop.
title_full_unstemmed	A role for programmed cell death in the microbial loop.
title_sort	role for programmed cell death in the microbial loop.
publisher	Public Library of Science (PLoS)
publishDate	2013
url	https://doaj.org/article/20b4d952847c4733b6389ec7e5b8db4a
work_keys_str_mv	AT monicavorellana aroleforprogrammedcelldeathinthemicrobialloop AT wyminglpang aroleforprogrammedcelldeathinthemicrobialloop AT pierremdurand aroleforprogrammedcelldeathinthemicrobialloop AT keniawhitehead aroleforprogrammedcelldeathinthemicrobialloop AT nitinsbaliga aroleforprogrammedcelldeathinthemicrobialloop AT monicavorellana roleforprogrammedcelldeathinthemicrobialloop AT wyminglpang roleforprogrammedcelldeathinthemicrobialloop AT pierremdurand roleforprogrammedcelldeathinthemicrobialloop AT keniawhitehead roleforprogrammedcelldeathinthemicrobialloop AT nitinsbaliga roleforprogrammedcelldeathinthemicrobialloop
_version_	1718422959027126272

A role for programmed cell death in the microbial loop.

Ejemplares similares