Aromatic C-H addition of ketones to imines enabled by manganese catalysis
The Mannich reaction proceeds by functionalization of C(sp3)-H bonds alpha to carbonyls. Here, the authors suppress the Mannich reactivity of acetophenones in presence of a manganese catalyst and obtain valuable o-aminoalkylacetophenones and isoindolines via C(sp2)-H functionalization with imines.
Guardado en:
Autores principales: | , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/20c2a944a63746be8193d3b2717ff70f |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:20c2a944a63746be8193d3b2717ff70f |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:20c2a944a63746be8193d3b2717ff70f2021-12-02T14:42:16ZAromatic C-H addition of ketones to imines enabled by manganese catalysis10.1038/s41467-017-01262-42041-1723https://doaj.org/article/20c2a944a63746be8193d3b2717ff70f2017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01262-4https://doaj.org/toc/2041-1723The Mannich reaction proceeds by functionalization of C(sp3)-H bonds alpha to carbonyls. Here, the authors suppress the Mannich reactivity of acetophenones in presence of a manganese catalyst and obtain valuable o-aminoalkylacetophenones and isoindolines via C(sp2)-H functionalization with imines.Bingwei ZhouYuanyuan HuTing LiuCongyang WangNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Bingwei Zhou Yuanyuan Hu Ting Liu Congyang Wang Aromatic C-H addition of ketones to imines enabled by manganese catalysis |
description |
The Mannich reaction proceeds by functionalization of C(sp3)-H bonds alpha to carbonyls. Here, the authors suppress the Mannich reactivity of acetophenones in presence of a manganese catalyst and obtain valuable o-aminoalkylacetophenones and isoindolines via C(sp2)-H functionalization with imines. |
format |
article |
author |
Bingwei Zhou Yuanyuan Hu Ting Liu Congyang Wang |
author_facet |
Bingwei Zhou Yuanyuan Hu Ting Liu Congyang Wang |
author_sort |
Bingwei Zhou |
title |
Aromatic C-H addition of ketones to imines enabled by manganese catalysis |
title_short |
Aromatic C-H addition of ketones to imines enabled by manganese catalysis |
title_full |
Aromatic C-H addition of ketones to imines enabled by manganese catalysis |
title_fullStr |
Aromatic C-H addition of ketones to imines enabled by manganese catalysis |
title_full_unstemmed |
Aromatic C-H addition of ketones to imines enabled by manganese catalysis |
title_sort |
aromatic c-h addition of ketones to imines enabled by manganese catalysis |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/20c2a944a63746be8193d3b2717ff70f |
work_keys_str_mv |
AT bingweizhou aromaticchadditionofketonestoiminesenabledbymanganesecatalysis AT yuanyuanhu aromaticchadditionofketonestoiminesenabledbymanganesecatalysis AT tingliu aromaticchadditionofketonestoiminesenabledbymanganesecatalysis AT congyangwang aromaticchadditionofketonestoiminesenabledbymanganesecatalysis |
_version_ |
1718389738280321024 |