The integrated genomic and epigenomic landscape of brainstem glioma

The integrated genomic and epigenomic landscape of brainstem glioma

Brainstem gliomas are heterogenous in terms of clinical outcome and disease etiology. Here, the authors present a genetic and epigenetic landscape of brainstem gliomas, finding distinct epigenetic clusters associated with unique genetic and clinical profiles.

Guardado en:
Detalles Bibliográficos
Autores principales: Lee H. Chen, Changcun Pan, Bill H. Diplas, Cheng Xu, Landon J. Hansen, Yuliang Wu, Xin Chen, Yibo Geng, Tao Sun, Yu Sun, Peng Zhang, Zhen Wu, Junting Zhang, Deling Li, Yang Zhang, Wenhao Wu, Yu Wang, Guangyu Li, Jie Yang, Xiaoyue Wang, Ce Xu, Sizhen Wang, Matthew S. Waitkus, Yiping He, Roger E. McLendon, David M. Ashley, Hai Yan, Liwei Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/20c3ed793a784a5b8bd512a9238d11e8
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:20c3ed793a784a5b8bd512a9238d11e8
record_format dspace
spelling oai:doaj.org-article:20c3ed793a784a5b8bd512a9238d11e82021-12-02T17:23:25ZThe integrated genomic and epigenomic landscape of brainstem glioma10.1038/s41467-020-16682-y2041-1723https://doaj.org/article/20c3ed793a784a5b8bd512a9238d11e82020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16682-yhttps://doaj.org/toc/2041-1723Brainstem gliomas are heterogenous in terms of clinical outcome and disease etiology. Here, the authors present a genetic and epigenetic landscape of brainstem gliomas, finding distinct epigenetic clusters associated with unique genetic and clinical profiles.Lee H. ChenChangcun PanBill H. DiplasCheng XuLandon J. HansenYuliang WuXin ChenYibo GengTao SunYu SunPeng ZhangZhen WuJunting ZhangDeling LiYang ZhangWenhao WuYu WangGuangyu LiJie YangXiaoyue WangCe XuSizhen WangMatthew S. WaitkusYiping HeRoger E. McLendonDavid M. AshleyHai YanLiwei ZhangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Lee H. Chen
Changcun Pan
Bill H. Diplas
Cheng Xu
Landon J. Hansen
Yuliang Wu
Xin Chen
Yibo Geng
Tao Sun
Yu Sun
Peng Zhang
Zhen Wu
Junting Zhang
Deling Li
Yang Zhang
Wenhao Wu
Yu Wang
Guangyu Li
Jie Yang
Xiaoyue Wang
Ce Xu
Sizhen Wang
Matthew S. Waitkus
Yiping He
Roger E. McLendon
David M. Ashley
Hai Yan
Liwei Zhang
The integrated genomic and epigenomic landscape of brainstem glioma
description Brainstem gliomas are heterogenous in terms of clinical outcome and disease etiology. Here, the authors present a genetic and epigenetic landscape of brainstem gliomas, finding distinct epigenetic clusters associated with unique genetic and clinical profiles.
format article
author Lee H. Chen
Changcun Pan
Bill H. Diplas
Cheng Xu
Landon J. Hansen
Yuliang Wu
Xin Chen
Yibo Geng
Tao Sun
Yu Sun
Peng Zhang
Zhen Wu
Junting Zhang
Deling Li
Yang Zhang
Wenhao Wu
Yu Wang
Guangyu Li
Jie Yang
Xiaoyue Wang
Ce Xu
Sizhen Wang
Matthew S. Waitkus
Yiping He
Roger E. McLendon
David M. Ashley
Hai Yan
Liwei Zhang
author_facet Lee H. Chen
Changcun Pan
Bill H. Diplas
Cheng Xu
Landon J. Hansen
Yuliang Wu
Xin Chen
Yibo Geng
Tao Sun
Yu Sun
Peng Zhang
Zhen Wu
Junting Zhang
Deling Li
Yang Zhang
Wenhao Wu
Yu Wang
Guangyu Li
Jie Yang
Xiaoyue Wang
Ce Xu
Sizhen Wang
Matthew S. Waitkus
Yiping He
Roger E. McLendon
David M. Ashley
Hai Yan
Liwei Zhang
author_sort Lee H. Chen
title The integrated genomic and epigenomic landscape of brainstem glioma
title_short The integrated genomic and epigenomic landscape of brainstem glioma
title_full The integrated genomic and epigenomic landscape of brainstem glioma
title_fullStr The integrated genomic and epigenomic landscape of brainstem glioma
title_full_unstemmed The integrated genomic and epigenomic landscape of brainstem glioma
title_sort integrated genomic and epigenomic landscape of brainstem glioma
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/20c3ed793a784a5b8bd512a9238d11e8
work_keys_str_mv AT leehchen theintegratedgenomicandepigenomiclandscapeofbrainstemglioma
AT changcunpan theintegratedgenomicandepigenomiclandscapeofbrainstemglioma
AT billhdiplas theintegratedgenomicandepigenomiclandscapeofbrainstemglioma
AT chengxu theintegratedgenomicandepigenomiclandscapeofbrainstemglioma
AT landonjhansen theintegratedgenomicandepigenomiclandscapeofbrainstemglioma
AT yuliangwu theintegratedgenomicandepigenomiclandscapeofbrainstemglioma
AT xinchen theintegratedgenomicandepigenomiclandscapeofbrainstemglioma
AT yibogeng theintegratedgenomicandepigenomiclandscapeofbrainstemglioma
AT taosun theintegratedgenomicandepigenomiclandscapeofbrainstemglioma
AT yusun theintegratedgenomicandepigenomiclandscapeofbrainstemglioma
AT pengzhang theintegratedgenomicandepigenomiclandscapeofbrainstemglioma
AT zhenwu theintegratedgenomicandepigenomiclandscapeofbrainstemglioma
AT juntingzhang theintegratedgenomicandepigenomiclandscapeofbrainstemglioma
AT delingli theintegratedgenomicandepigenomiclandscapeofbrainstemglioma
AT yangzhang theintegratedgenomicandepigenomiclandscapeofbrainstemglioma
AT wenhaowu theintegratedgenomicandepigenomiclandscapeofbrainstemglioma
AT yuwang theintegratedgenomicandepigenomiclandscapeofbrainstemglioma
AT guangyuli theintegratedgenomicandepigenomiclandscapeofbrainstemglioma
AT jieyang theintegratedgenomicandepigenomiclandscapeofbrainstemglioma
AT xiaoyuewang theintegratedgenomicandepigenomiclandscapeofbrainstemglioma
AT cexu theintegratedgenomicandepigenomiclandscapeofbrainstemglioma
AT sizhenwang theintegratedgenomicandepigenomiclandscapeofbrainstemglioma
AT matthewswaitkus theintegratedgenomicandepigenomiclandscapeofbrainstemglioma
AT yipinghe theintegratedgenomicandepigenomiclandscapeofbrainstemglioma
AT rogeremclendon theintegratedgenomicandepigenomiclandscapeofbrainstemglioma
AT davidmashley theintegratedgenomicandepigenomiclandscapeofbrainstemglioma
AT haiyan theintegratedgenomicandepigenomiclandscapeofbrainstemglioma
AT liweizhang theintegratedgenomicandepigenomiclandscapeofbrainstemglioma
AT leehchen integratedgenomicandepigenomiclandscapeofbrainstemglioma
AT changcunpan integratedgenomicandepigenomiclandscapeofbrainstemglioma
AT billhdiplas integratedgenomicandepigenomiclandscapeofbrainstemglioma
AT chengxu integratedgenomicandepigenomiclandscapeofbrainstemglioma
AT landonjhansen integratedgenomicandepigenomiclandscapeofbrainstemglioma
AT yuliangwu integratedgenomicandepigenomiclandscapeofbrainstemglioma
AT xinchen integratedgenomicandepigenomiclandscapeofbrainstemglioma
AT yibogeng integratedgenomicandepigenomiclandscapeofbrainstemglioma
AT taosun integratedgenomicandepigenomiclandscapeofbrainstemglioma
AT yusun integratedgenomicandepigenomiclandscapeofbrainstemglioma
AT pengzhang integratedgenomicandepigenomiclandscapeofbrainstemglioma
AT zhenwu integratedgenomicandepigenomiclandscapeofbrainstemglioma
AT juntingzhang integratedgenomicandepigenomiclandscapeofbrainstemglioma
AT delingli integratedgenomicandepigenomiclandscapeofbrainstemglioma
AT yangzhang integratedgenomicandepigenomiclandscapeofbrainstemglioma
AT wenhaowu integratedgenomicandepigenomiclandscapeofbrainstemglioma
AT yuwang integratedgenomicandepigenomiclandscapeofbrainstemglioma
AT guangyuli integratedgenomicandepigenomiclandscapeofbrainstemglioma
AT jieyang integratedgenomicandepigenomiclandscapeofbrainstemglioma
AT xiaoyuewang integratedgenomicandepigenomiclandscapeofbrainstemglioma
AT cexu integratedgenomicandepigenomiclandscapeofbrainstemglioma
AT sizhenwang integratedgenomicandepigenomiclandscapeofbrainstemglioma
AT matthewswaitkus integratedgenomicandepigenomiclandscapeofbrainstemglioma
AT yipinghe integratedgenomicandepigenomiclandscapeofbrainstemglioma
AT rogeremclendon integratedgenomicandepigenomiclandscapeofbrainstemglioma
AT davidmashley integratedgenomicandepigenomiclandscapeofbrainstemglioma
AT haiyan integratedgenomicandepigenomiclandscapeofbrainstemglioma
AT liweizhang integratedgenomicandepigenomiclandscapeofbrainstemglioma
_version_ 1718380957237510144

Ejemplares similares