The Microbiota Promotes Arterial Thrombosis in Low-Density Lipoprotein Receptor-Deficient Mice

The Microbiota Promotes Arterial Thrombosis in Low-Density Lipoprotein Receptor-Deficient Mice

ABSTRACT Atherosclerotic plaque development depends on chronic inflammation of the arterial wall. A dysbiotic gut microbiota can cause low-grade inflammation, and microbiota composition was linked to cardiovascular disease risk. However, the role of this environmental factor in atherothrombosis rema...

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Autores principales: Klytaimnistra Kiouptsi, Sven Jäckel, Giulia Pontarollo, Alexandra Grill, Marijke J. E. Kuijpers, Eivor Wilms, Christian Weber, Felix Sommer, Magdolna Nagy, Carlos Neideck, Yvonne Jansen, Stefanie Ascher, Henning Formes, Cornelia Karwot, Franziska Bayer, Bettina Kollar, Saravanan Subramaniam, Michael Molitor, Philip Wenzel, Philip Rosenstiel, Hristo Todorov, Susanne Gerber, Ulrich Walter, Kerstin Jurk, Johan W. M. Heemskerk, Emiel P. C. van der Vorst, Yvonne Döring, Christoph Reinhardt
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
Materias:
gut microbiota
germfree
low-density lipoprotein receptor
arterial thrombosis
atherothrombosis
carotid artery
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/20c67fc195d04a29b3eecc489e3dc276
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