Unique structure and function of viral rhodopsins

Rhodopsin genes have been identified in some large double-stranded DNA viruses, but the structure and functions of viral rhodopsins remain unknown. Here authors present crystal structure and characterization of an Organic Lake Phycodnavirus rhodopsin II (OLPVRII) which forms a pentamer and is a weak...

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Autores principales: Dmitry Bratanov, Kirill Kovalev, Jan-Philipp Machtens, Roman Astashkin, Igor Chizhov, Dmytro Soloviov, Dmytro Volkov, Vitaly Polovinkin, Dmitrii Zabelskii, Thomas Mager, Ivan Gushchin, Tatyana Rokitskaya, Yuri Antonenko, Alexey Alekseev, Vitaly Shevchenko, Natalya Yutin, Riccardo Rosselli, Christian Baeken, Valentin Borshchevskiy, Gleb Bourenkov, Alexander Popov, Taras Balandin, Georg Büldt, Dietmar J. Manstein, Francisco Rodriguez-Valera, Christoph Fahlke, Ernst Bamberg, Eugene Koonin, Valentin Gordeliy
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/20ce96168fbe41fdba6908ad7848aa9e
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Sumario:Rhodopsin genes have been identified in some large double-stranded DNA viruses, but the structure and functions of viral rhodopsins remain unknown. Here authors present crystal structure and characterization of an Organic Lake Phycodnavirus rhodopsin II (OLPVRII) which forms a pentamer and is a weak proton pump.