Serial processing of kinematic signals by cerebellar circuitry during voluntary whisking
Cerebellar Purkinje cells (PCs) linearly encode whisker position but the precise circuit mechanisms that generate these signals are not well understood. Here the authors use patch clamp recordings to show that selective tuning of granule cell inputs and bidirectional tuning of interneuron inputs are...
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Nature Portfolio
2017
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oai:doaj.org-article:20e260e620ab437db7eed40df84a17ee2021-12-02T10:48:10ZSerial processing of kinematic signals by cerebellar circuitry during voluntary whisking10.1038/s41467-017-00312-12041-1723https://doaj.org/article/20e260e620ab437db7eed40df84a17ee2017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00312-1https://doaj.org/toc/2041-1723Cerebellar Purkinje cells (PCs) linearly encode whisker position but the precise circuit mechanisms that generate these signals are not well understood. Here the authors use patch clamp recordings to show that selective tuning of granule cell inputs and bidirectional tuning of interneuron inputs are required to generate the kinematic representations in PCs.Susu ChenGeorge J. AugustinePaul ChaddertonNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017) |
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Science Q Susu Chen George J. Augustine Paul Chadderton Serial processing of kinematic signals by cerebellar circuitry during voluntary whisking |
description |
Cerebellar Purkinje cells (PCs) linearly encode whisker position but the precise circuit mechanisms that generate these signals are not well understood. Here the authors use patch clamp recordings to show that selective tuning of granule cell inputs and bidirectional tuning of interneuron inputs are required to generate the kinematic representations in PCs. |
format |
article |
author |
Susu Chen George J. Augustine Paul Chadderton |
author_facet |
Susu Chen George J. Augustine Paul Chadderton |
author_sort |
Susu Chen |
title |
Serial processing of kinematic signals by cerebellar circuitry during voluntary whisking |
title_short |
Serial processing of kinematic signals by cerebellar circuitry during voluntary whisking |
title_full |
Serial processing of kinematic signals by cerebellar circuitry during voluntary whisking |
title_fullStr |
Serial processing of kinematic signals by cerebellar circuitry during voluntary whisking |
title_full_unstemmed |
Serial processing of kinematic signals by cerebellar circuitry during voluntary whisking |
title_sort |
serial processing of kinematic signals by cerebellar circuitry during voluntary whisking |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/20e260e620ab437db7eed40df84a17ee |
work_keys_str_mv |
AT susuchen serialprocessingofkinematicsignalsbycerebellarcircuitryduringvoluntarywhisking AT georgejaugustine serialprocessingofkinematicsignalsbycerebellarcircuitryduringvoluntarywhisking AT paulchadderton serialprocessingofkinematicsignalsbycerebellarcircuitryduringvoluntarywhisking |
_version_ |
1718396635257503744 |