Preoperative clinical and tumor genomic features associated with pathologic lymph node metastasis in clinical stage I and II lung adenocarcinoma

Preoperative clinical and tumor genomic features associated with pathologic lymph node metastasis in clinical stage I and II lung adenocarcinoma

Abstract While next-generation sequencing (NGS) is used to guide therapy in patients with metastatic lung adenocarcinoma (LUAD), use of NGS to determine pathologic LN metastasis prior to surgery has not been assessed. To bridge this knowledge gap, we performed NGS using MSK-IMPACT in 426 treatment-n...

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Autores principales: Raul Caso, James G. Connolly, Jian Zhou, Kay See Tan, James J. Choi, Gregory D. Jones, Brooke Mastrogiacomo, Francisco Sanchez-Vega, Bastien Nguyen, Gaetano Rocco, Daniela Molena, Smita Sihag, Prasad S. Adusumilli, Matthew J. Bott, David R. Jones
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Acceso en línea:https://doaj.org/article/20e2c3f365ef4a4b89f96ace034d68c1
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