Full-length L1CAM and not its Δ2Δ27 splice variant promotes metastasis through induction of gelatinase expression.

Tumour-specific splicing is known to contribute to cancer progression. In the case of the L1 cell adhesion molecule (L1CAM), which is expressed in many human tumours and often linked to bad prognosis, alternative splicing results in a full-length form (FL-L1CAM) and a splice variant lacking exons 2...

Description complète

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Stephanie Hauser, Laura Bickel, Dirk Weinspach, Michael Gerg, Michael K Schäfer, Marco Pfeifer, John Hazin, Florian Schelter, Ulrich H Weidle, Juliane Ramser, Juliane Volkmann, Alfons Meindl, Manfred Schmitt, Florian Schrötzlmair, Peter Altevogt, Achim Krüger
Format:	article
Langue:	EN
Publié:	Public Library of Science (PLoS) 2011
Sujets:	Medicine R Science Q
Accès en ligne:	https://doaj.org/article/20e94dbc38a8494ea8dea37e22a7e445
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

Soyez le premier à ajouter un commentaire!

Full-length L1CAM and not its Δ2Δ27 splice variant promotes metastasis through induction of gelatinase expression.

Documents similaires