Investigating single amino acid substitutions in PIM1 kinase: A structural genomics approach.

Investigating single amino acid substitutions in PIM1 kinase: A structural genomics approach.

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PIM1, is a serine/threonine proto-oncogene kinase, involved in many biological functions, including cell survival, proliferation, and differentiation, thus play a key role in oncogenesis. It plays a crucial role in the onset and progression of various hematopoietic and non-hematopoietic malignancies...

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Autores principales: Alaa Shafie, Shama Khan, Sagar Batra, Farah Anjum, Taj Mohammad, Shoaib Alam, Dharmendra Kumar Yadav, Asimul Islam, Md Imtaiyaz Hassan
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/20ea66356c824631b95621659e698cf5
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