Reference intervals and values for fecal cortisol, aldosterone, and the ratio of cortisol to dehydroepiandrosterone metabolites in four species of cetaceans.

The goal of the current study was to create reference intervals and values for several common and one potential novel physiological indicators of animal welfare for four species of cetaceans. The subjects included 189 bottlenose dolphins (Tursiops truncatus), 27 Indo-Pacific bottlenose dolphins (Tur...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Lance J Miller, Lisa K Lauderdale, Michael T Walsh, Jocelyn L Bryant, Kevin A Mitchell, Douglas A Granger, Jill D Mellen
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/20fc15b45a824197929ac30b70dc94a1
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:20fc15b45a824197929ac30b70dc94a1
record_format	dspace
spelling	oai:doaj.org-article:20fc15b45a824197929ac30b70dc94a12021-12-02T20:14:52ZReference intervals and values for fecal cortisol, aldosterone, and the ratio of cortisol to dehydroepiandrosterone metabolites in four species of cetaceans.1932-620310.1371/journal.pone.0250331https://doaj.org/article/20fc15b45a824197929ac30b70dc94a12021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0250331https://doaj.org/toc/1932-6203The goal of the current study was to create reference intervals and values for several common and one potential novel physiological indicators of animal welfare for four species of cetaceans. The subjects included 189 bottlenose dolphins (Tursiops truncatus), 27 Indo-Pacific bottlenose dolphins (Tursiops aduncus), eight Pacific white-sided dolphins (Lagenorhynchus obliquidens), and 13 beluga whales (Delphinapterus leucas) at Alliance of Marine Mammal Parks and Aquariums and/or Association of Zoos and Aquariums accredited facilities. During two sampling time periods between July and November of 2018 and between January and April of 2019, fecal samples were collected weekly for five weeks from all animals. Samples were processed and analyzed using enzyme immunoassay for fecal cortisol, aldosterone, and dehydroepiandrosterone (DHEA) metabolites. Linear mixed models were used to examine demographic and time factors impacting hormone metabolite concentrations. Age, sex, and time of year were all significant predictors for some of the models (p < 0.01). An iOS mobile application ZooPhysioTrak was created for easy access to species-specific reference intervals and values accounting for significant predictors. For facilities without access to this application, additional reference intervals and values were constructed without accounting for significant predictors. Information gained from this study and the use of the application can provide reference intervals and values to make informed management decisions for cetaceans in zoological facilities.Lance J MillerLisa K LauderdaleMichael T WalshJocelyn L BryantKevin A MitchellDouglas A GrangerJill D MellenPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 8, p e0250331 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Lance J Miller Lisa K Lauderdale Michael T Walsh Jocelyn L Bryant Kevin A Mitchell Douglas A Granger Jill D Mellen Reference intervals and values for fecal cortisol, aldosterone, and the ratio of cortisol to dehydroepiandrosterone metabolites in four species of cetaceans.
description	The goal of the current study was to create reference intervals and values for several common and one potential novel physiological indicators of animal welfare for four species of cetaceans. The subjects included 189 bottlenose dolphins (Tursiops truncatus), 27 Indo-Pacific bottlenose dolphins (Tursiops aduncus), eight Pacific white-sided dolphins (Lagenorhynchus obliquidens), and 13 beluga whales (Delphinapterus leucas) at Alliance of Marine Mammal Parks and Aquariums and/or Association of Zoos and Aquariums accredited facilities. During two sampling time periods between July and November of 2018 and between January and April of 2019, fecal samples were collected weekly for five weeks from all animals. Samples were processed and analyzed using enzyme immunoassay for fecal cortisol, aldosterone, and dehydroepiandrosterone (DHEA) metabolites. Linear mixed models were used to examine demographic and time factors impacting hormone metabolite concentrations. Age, sex, and time of year were all significant predictors for some of the models (p < 0.01). An iOS mobile application ZooPhysioTrak was created for easy access to species-specific reference intervals and values accounting for significant predictors. For facilities without access to this application, additional reference intervals and values were constructed without accounting for significant predictors. Information gained from this study and the use of the application can provide reference intervals and values to make informed management decisions for cetaceans in zoological facilities.
format	article
author	Lance J Miller Lisa K Lauderdale Michael T Walsh Jocelyn L Bryant Kevin A Mitchell Douglas A Granger Jill D Mellen
author_facet	Lance J Miller Lisa K Lauderdale Michael T Walsh Jocelyn L Bryant Kevin A Mitchell Douglas A Granger Jill D Mellen
author_sort	Lance J Miller
title	Reference intervals and values for fecal cortisol, aldosterone, and the ratio of cortisol to dehydroepiandrosterone metabolites in four species of cetaceans.
title_short	Reference intervals and values for fecal cortisol, aldosterone, and the ratio of cortisol to dehydroepiandrosterone metabolites in four species of cetaceans.
title_full	Reference intervals and values for fecal cortisol, aldosterone, and the ratio of cortisol to dehydroepiandrosterone metabolites in four species of cetaceans.
title_fullStr	Reference intervals and values for fecal cortisol, aldosterone, and the ratio of cortisol to dehydroepiandrosterone metabolites in four species of cetaceans.
title_full_unstemmed	Reference intervals and values for fecal cortisol, aldosterone, and the ratio of cortisol to dehydroepiandrosterone metabolites in four species of cetaceans.
title_sort	reference intervals and values for fecal cortisol, aldosterone, and the ratio of cortisol to dehydroepiandrosterone metabolites in four species of cetaceans.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/20fc15b45a824197929ac30b70dc94a1
work_keys_str_mv	AT lancejmiller referenceintervalsandvaluesforfecalcortisolaldosteroneandtheratioofcortisoltodehydroepiandrosteronemetabolitesinfourspeciesofcetaceans AT lisaklauderdale referenceintervalsandvaluesforfecalcortisolaldosteroneandtheratioofcortisoltodehydroepiandrosteronemetabolitesinfourspeciesofcetaceans AT michaeltwalsh referenceintervalsandvaluesforfecalcortisolaldosteroneandtheratioofcortisoltodehydroepiandrosteronemetabolitesinfourspeciesofcetaceans AT jocelynlbryant referenceintervalsandvaluesforfecalcortisolaldosteroneandtheratioofcortisoltodehydroepiandrosteronemetabolitesinfourspeciesofcetaceans AT kevinamitchell referenceintervalsandvaluesforfecalcortisolaldosteroneandtheratioofcortisoltodehydroepiandrosteronemetabolitesinfourspeciesofcetaceans AT douglasagranger referenceintervalsandvaluesforfecalcortisolaldosteroneandtheratioofcortisoltodehydroepiandrosteronemetabolitesinfourspeciesofcetaceans AT jilldmellen referenceintervalsandvaluesforfecalcortisolaldosteroneandtheratioofcortisoltodehydroepiandrosteronemetabolitesinfourspeciesofcetaceans
_version_	1718374632235466752

Reference intervals and values for fecal cortisol, aldosterone, and the ratio of cortisol to dehydroepiandrosterone metabolites in four species of cetaceans.

Ejemplares similares