Inhibition of extracellular vesicle-associated MMP2 abrogates intercellular hepatic miR-122 transfer to liver macrophages and curtails inflammation

Inhibition of extracellular vesicle-associated MMP2 abrogates intercellular hepatic miR-122 transfer to liver macrophages and curtails inflammation

Summary: Hepatic miRNA, miR-122, plays an important role in controlling metabolic homeostasis in mammalian liver. Intercellular transfer of miR-122 was found to play a role in controlling tissue inflammation. miR-122, as part of extracellular vesicles released by lipid-exposed hepatic cells, are tak...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Arnab Das, Sudarshana Basu, Diptankar Bandyopadhyay, Kamalika Mukherjee, Debduti Datta, Sreemoyee Chakraborty, Sayantan Jana, Moumita Adak, Sarpita Bose, Saikat Chakrabarti, Snehasikta Swarnakar, Partha Chakrabarti, Suvendra N. Bhattacharyya
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
Materias:
Biological sciences
Molecular biology
Immunology
Science
Q
Acceso en línea:https://doaj.org/article/20ff895894664ecf8a178c647c642da8
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Internet

https://doaj.org/article/20ff895894664ecf8a178c647c642da8

Ejemplares similares