Proteasome, but not autophagy, disruption results in severe eye and wing dysmorphia: a subunit- and regulator-dependent process in Drosophila.

Proteasome-dependent and autophagy-mediated degradation of eukaryotic cellular proteins represent the two major proteostatic mechanisms that are critically implicated in a number of signaling pathways and cellular processes. Deregulation of functions engaged in protein elimination frequently leads t...

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Autores principales: Panagiotis D Velentzas, Athanassios D Velentzas, Asimina D Pantazi, Vassiliki E Mpakou, Christos G Zervas, Issidora S Papassideri, Dimitrios J Stravopodis
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/2104d1475fc6433480c01794c3ae7ab3
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