TRPV1 regulates excitatory innervation of OLM neurons in the hippocampus
The role of TRPV1 in the CNS is not fully understood. Here the authors show that TRPV1 is expressed specifically in somatostatin-positive OLM interneurons of the hippocampus, where it promotes excitatory innervation of these cells.
Guardado en:
Autores principales: | , , , , , , , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/2105af867abe4a79822bee9ec7df90cb |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:2105af867abe4a79822bee9ec7df90cb |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:2105af867abe4a79822bee9ec7df90cb2021-12-02T14:40:48ZTRPV1 regulates excitatory innervation of OLM neurons in the hippocampus10.1038/ncomms158782041-1723https://doaj.org/article/2105af867abe4a79822bee9ec7df90cb2017-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms15878https://doaj.org/toc/2041-1723The role of TRPV1 in the CNS is not fully understood. Here the authors show that TRPV1 is expressed specifically in somatostatin-positive OLM interneurons of the hippocampus, where it promotes excitatory innervation of these cells.Joaquin I. Hurtado-ZavalaBinu RamachandranSaheeb AhmedRashi HalderChristiane BolleyerAnkit AwasthiMarkus A. StahlbergRobin J. WagenerKristin AndersonRyan M. DrenanHenry A. LesterJulie M. MiwaJochen F. StaigerAndre FischerCamin DeanNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-20 (2017) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Joaquin I. Hurtado-Zavala Binu Ramachandran Saheeb Ahmed Rashi Halder Christiane Bolleyer Ankit Awasthi Markus A. Stahlberg Robin J. Wagener Kristin Anderson Ryan M. Drenan Henry A. Lester Julie M. Miwa Jochen F. Staiger Andre Fischer Camin Dean TRPV1 regulates excitatory innervation of OLM neurons in the hippocampus |
description |
The role of TRPV1 in the CNS is not fully understood. Here the authors show that TRPV1 is expressed specifically in somatostatin-positive OLM interneurons of the hippocampus, where it promotes excitatory innervation of these cells. |
format |
article |
author |
Joaquin I. Hurtado-Zavala Binu Ramachandran Saheeb Ahmed Rashi Halder Christiane Bolleyer Ankit Awasthi Markus A. Stahlberg Robin J. Wagener Kristin Anderson Ryan M. Drenan Henry A. Lester Julie M. Miwa Jochen F. Staiger Andre Fischer Camin Dean |
author_facet |
Joaquin I. Hurtado-Zavala Binu Ramachandran Saheeb Ahmed Rashi Halder Christiane Bolleyer Ankit Awasthi Markus A. Stahlberg Robin J. Wagener Kristin Anderson Ryan M. Drenan Henry A. Lester Julie M. Miwa Jochen F. Staiger Andre Fischer Camin Dean |
author_sort |
Joaquin I. Hurtado-Zavala |
title |
TRPV1 regulates excitatory innervation of OLM neurons in the hippocampus |
title_short |
TRPV1 regulates excitatory innervation of OLM neurons in the hippocampus |
title_full |
TRPV1 regulates excitatory innervation of OLM neurons in the hippocampus |
title_fullStr |
TRPV1 regulates excitatory innervation of OLM neurons in the hippocampus |
title_full_unstemmed |
TRPV1 regulates excitatory innervation of OLM neurons in the hippocampus |
title_sort |
trpv1 regulates excitatory innervation of olm neurons in the hippocampus |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/2105af867abe4a79822bee9ec7df90cb |
work_keys_str_mv |
AT joaquinihurtadozavala trpv1regulatesexcitatoryinnervationofolmneuronsinthehippocampus AT binuramachandran trpv1regulatesexcitatoryinnervationofolmneuronsinthehippocampus AT saheebahmed trpv1regulatesexcitatoryinnervationofolmneuronsinthehippocampus AT rashihalder trpv1regulatesexcitatoryinnervationofolmneuronsinthehippocampus AT christianebolleyer trpv1regulatesexcitatoryinnervationofolmneuronsinthehippocampus AT ankitawasthi trpv1regulatesexcitatoryinnervationofolmneuronsinthehippocampus AT markusastahlberg trpv1regulatesexcitatoryinnervationofolmneuronsinthehippocampus AT robinjwagener trpv1regulatesexcitatoryinnervationofolmneuronsinthehippocampus AT kristinanderson trpv1regulatesexcitatoryinnervationofolmneuronsinthehippocampus AT ryanmdrenan trpv1regulatesexcitatoryinnervationofolmneuronsinthehippocampus AT henryalester trpv1regulatesexcitatoryinnervationofolmneuronsinthehippocampus AT juliemmiwa trpv1regulatesexcitatoryinnervationofolmneuronsinthehippocampus AT jochenfstaiger trpv1regulatesexcitatoryinnervationofolmneuronsinthehippocampus AT andrefischer trpv1regulatesexcitatoryinnervationofolmneuronsinthehippocampus AT camindean trpv1regulatesexcitatoryinnervationofolmneuronsinthehippocampus |
_version_ |
1718390098846810112 |