TRPV1 regulates excitatory innervation of OLM neurons in the hippocampus

The role of TRPV1 in the CNS is not fully understood. Here the authors show that TRPV1 is expressed specifically in somatostatin-positive OLM interneurons of the hippocampus, where it promotes excitatory innervation of these cells.

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Autores principales: Joaquin I. Hurtado-Zavala, Binu Ramachandran, Saheeb Ahmed, Rashi Halder, Christiane Bolleyer, Ankit Awasthi, Markus A. Stahlberg, Robin J. Wagener, Kristin Anderson, Ryan M. Drenan, Henry A. Lester, Julie M. Miwa, Jochen F. Staiger, Andre Fischer, Camin Dean
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/2105af867abe4a79822bee9ec7df90cb
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spelling oai:doaj.org-article:2105af867abe4a79822bee9ec7df90cb2021-12-02T14:40:48ZTRPV1 regulates excitatory innervation of OLM neurons in the hippocampus10.1038/ncomms158782041-1723https://doaj.org/article/2105af867abe4a79822bee9ec7df90cb2017-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms15878https://doaj.org/toc/2041-1723The role of TRPV1 in the CNS is not fully understood. Here the authors show that TRPV1 is expressed specifically in somatostatin-positive OLM interneurons of the hippocampus, where it promotes excitatory innervation of these cells.Joaquin I. Hurtado-ZavalaBinu RamachandranSaheeb AhmedRashi HalderChristiane BolleyerAnkit AwasthiMarkus A. StahlbergRobin J. WagenerKristin AndersonRyan M. DrenanHenry A. LesterJulie M. MiwaJochen F. StaigerAndre FischerCamin DeanNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-20 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Joaquin I. Hurtado-Zavala
Binu Ramachandran
Saheeb Ahmed
Rashi Halder
Christiane Bolleyer
Ankit Awasthi
Markus A. Stahlberg
Robin J. Wagener
Kristin Anderson
Ryan M. Drenan
Henry A. Lester
Julie M. Miwa
Jochen F. Staiger
Andre Fischer
Camin Dean
TRPV1 regulates excitatory innervation of OLM neurons in the hippocampus
description The role of TRPV1 in the CNS is not fully understood. Here the authors show that TRPV1 is expressed specifically in somatostatin-positive OLM interneurons of the hippocampus, where it promotes excitatory innervation of these cells.
format article
author Joaquin I. Hurtado-Zavala
Binu Ramachandran
Saheeb Ahmed
Rashi Halder
Christiane Bolleyer
Ankit Awasthi
Markus A. Stahlberg
Robin J. Wagener
Kristin Anderson
Ryan M. Drenan
Henry A. Lester
Julie M. Miwa
Jochen F. Staiger
Andre Fischer
Camin Dean
author_facet Joaquin I. Hurtado-Zavala
Binu Ramachandran
Saheeb Ahmed
Rashi Halder
Christiane Bolleyer
Ankit Awasthi
Markus A. Stahlberg
Robin J. Wagener
Kristin Anderson
Ryan M. Drenan
Henry A. Lester
Julie M. Miwa
Jochen F. Staiger
Andre Fischer
Camin Dean
author_sort Joaquin I. Hurtado-Zavala
title TRPV1 regulates excitatory innervation of OLM neurons in the hippocampus
title_short TRPV1 regulates excitatory innervation of OLM neurons in the hippocampus
title_full TRPV1 regulates excitatory innervation of OLM neurons in the hippocampus
title_fullStr TRPV1 regulates excitatory innervation of OLM neurons in the hippocampus
title_full_unstemmed TRPV1 regulates excitatory innervation of OLM neurons in the hippocampus
title_sort trpv1 regulates excitatory innervation of olm neurons in the hippocampus
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/2105af867abe4a79822bee9ec7df90cb
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