Residue 6.43 defines receptor function in class F GPCRs
The class Frizzled of G protein-coupled receptors (GPCRs) consist of ten Frizzled (FZD1-10) subtypes and Smoothened (SMO). Here the Schulte laboratory demonstrates that FZDs differ substantially from SMO in receptor activation-associated conformational changes, while SMO manifests a preference for a...
Enregistré dans:
Auteurs principaux: | Ainoleena Turku, Hannes Schihada, Pawel Kozielewicz, Carl-Fredrik Bowin, Gunnar Schulte |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/210a27d0ce7040bd89c4edb6636fa89d |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Structural insight into small molecule action on Frizzleds
par: Paweł Kozielewicz, et autres
Publié: (2020) -
A conserved molecular switch in Class F receptors regulates receptor activation and pathway selection
par: Shane C. Wright, et autres
Publié: (2019) -
Acta Nº643
par: Banco Central de Chile
Publié: (2019) -
The origin of GPCRs: identification of mammalian like Rhodopsin, Adhesion, Glutamate and Frizzled GPCRs in fungi.
par: Arunkumar Krishnan, et autres
Publié: (2012) -
Resolution 643(XXXII) Place of the next session
Publié: (2014)