A conserved motif in JNK/p38-specific MAPK phosphatases as a determinant for JNK1 recognition and inactivation

The important MAPK family of signalling proteins is controlled by MAPK phosphatases (MKPs). Here, the authors report the structure of MKP7 bound to JNK1 and characterise the conserved MKP-MAPK interaction.

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Autores principales:	Xin Liu, Chen-Song Zhang, Chang Lu, Sheng-Cai Lin, Jia-Wei Wu, Zhi-Xin Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2110225295dc4b0a93ac6e2d8aecc2ae
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spelling	oai:doaj.org-article:2110225295dc4b0a93ac6e2d8aecc2ae2021-12-02T17:31:19ZA conserved motif in JNK/p38-specific MAPK phosphatases as a determinant for JNK1 recognition and inactivation10.1038/ncomms108792041-1723https://doaj.org/article/2110225295dc4b0a93ac6e2d8aecc2ae2016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms10879https://doaj.org/toc/2041-1723The important MAPK family of signalling proteins is controlled by MAPK phosphatases (MKPs). Here, the authors report the structure of MKP7 bound to JNK1 and characterise the conserved MKP-MAPK interaction.Xin LiuChen-Song ZhangChang LuSheng-Cai LinJia-Wei WuZhi-Xin WangNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xin Liu Chen-Song Zhang Chang Lu Sheng-Cai Lin Jia-Wei Wu Zhi-Xin Wang A conserved motif in JNK/p38-specific MAPK phosphatases as a determinant for JNK1 recognition and inactivation
description	The important MAPK family of signalling proteins is controlled by MAPK phosphatases (MKPs). Here, the authors report the structure of MKP7 bound to JNK1 and characterise the conserved MKP-MAPK interaction.
format	article
author	Xin Liu Chen-Song Zhang Chang Lu Sheng-Cai Lin Jia-Wei Wu Zhi-Xin Wang
author_facet	Xin Liu Chen-Song Zhang Chang Lu Sheng-Cai Lin Jia-Wei Wu Zhi-Xin Wang
author_sort	Xin Liu
title	A conserved motif in JNK/p38-specific MAPK phosphatases as a determinant for JNK1 recognition and inactivation
title_short	A conserved motif in JNK/p38-specific MAPK phosphatases as a determinant for JNK1 recognition and inactivation
title_full	A conserved motif in JNK/p38-specific MAPK phosphatases as a determinant for JNK1 recognition and inactivation
title_fullStr	A conserved motif in JNK/p38-specific MAPK phosphatases as a determinant for JNK1 recognition and inactivation
title_full_unstemmed	A conserved motif in JNK/p38-specific MAPK phosphatases as a determinant for JNK1 recognition and inactivation
title_sort	conserved motif in jnk/p38-specific mapk phosphatases as a determinant for jnk1 recognition and inactivation
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/2110225295dc4b0a93ac6e2d8aecc2ae
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A conserved motif in JNK/p38-specific MAPK phosphatases as a determinant for JNK1 recognition and inactivation

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