Incision wound healing activity of free-range chicken (Gallus domesticus) egg white gel in mice

Egg whites reportedly exhibit wound healing activities by forming new cell tissues and accelerating damaged cell tissue recovery. This study aimed to determine whether and how egg whites prepared in gel dosage forms healed incision wounds in mice (Mus musculus). The method began with formulating gel...

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Autores principales:	Wahyu Widyaningsih, Sapto Yuliani, Ayu Wulandari, Rifka Salsabila
Formato:	article
Lenguaje:	EN
Publicado:	Universitas Ahmad Dahlan 2021
Materias:	wound healing egg white gel incision Pharmacy and materia medica RS1-441
Acceso en línea:	https://doaj.org/article/211afe715ad8466b92f45ac98f8ba8aa
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spelling	oai:doaj.org-article:211afe715ad8466b92f45ac98f8ba8aa2021-11-17T05:23:18ZIncision wound healing activity of free-range chicken (Gallus domesticus) egg white gel in mice10.12928/pharmaciana.v11i3.205312088-45592477-0256https://doaj.org/article/211afe715ad8466b92f45ac98f8ba8aa2021-11-01T00:00:00Zhttp://journal.uad.ac.id/index.php/PHARMACIANA/article/view/20531/pdf_204https://doaj.org/toc/2088-4559https://doaj.org/toc/2477-0256Egg whites reportedly exhibit wound healing activities by forming new cell tissues and accelerating damaged cell tissue recovery. This study aimed to determine whether and how egg whites prepared in gel dosage forms healed incision wounds in mice (Mus musculus). The method began with formulating gels by mixing egg whites with Carbopol 940, methylparaben, propylparaben, propylene glycol, triethanolamine, and distilled water. Sixteen mice were divided evenly into four groups, and each was subjected to a 1 cm long midline dorsal incision. Group I was given 10% povidone-iodine ointment, group II was gel base, group III was 10% egg white gel, and group IV was 20% egg white gel. Based on the test parameters measured during macroscopic observation, namely wound length and healing time, the gel preparations were found to fulfill the physical properties requirements, and incision wounds treated with 10% and 20% egg white gels healed in 9 and 12.5 days, respectively. The statistical test revealed a significant difference in wound size on Day 10 and in healing time between wound treatments with 10% gel and base gel (p < 0.05). Therefore, it can be concluded that the 10% egg white gel is effective in healing cuts in mice as it speeds wound healing and decreases wound size.Wahyu WidyaningsihSapto Yuliani Sapto YulianiAyu WulandariRifka SalsabilaUniversitas Ahmad Dahlanarticlewound healingegg white gelincisionPharmacy and materia medicaRS1-441ENPharmaciana, Vol 11, Iss 3, Pp 321-329 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	wound healing egg white gel incision Pharmacy and materia medica RS1-441
spellingShingle	wound healing egg white gel incision Pharmacy and materia medica RS1-441 Wahyu Widyaningsih Sapto Yuliani Sapto Yuliani Ayu Wulandari Rifka Salsabila Incision wound healing activity of free-range chicken (Gallus domesticus) egg white gel in mice
description	Egg whites reportedly exhibit wound healing activities by forming new cell tissues and accelerating damaged cell tissue recovery. This study aimed to determine whether and how egg whites prepared in gel dosage forms healed incision wounds in mice (Mus musculus). The method began with formulating gels by mixing egg whites with Carbopol 940, methylparaben, propylparaben, propylene glycol, triethanolamine, and distilled water. Sixteen mice were divided evenly into four groups, and each was subjected to a 1 cm long midline dorsal incision. Group I was given 10% povidone-iodine ointment, group II was gel base, group III was 10% egg white gel, and group IV was 20% egg white gel. Based on the test parameters measured during macroscopic observation, namely wound length and healing time, the gel preparations were found to fulfill the physical properties requirements, and incision wounds treated with 10% and 20% egg white gels healed in 9 and 12.5 days, respectively. The statistical test revealed a significant difference in wound size on Day 10 and in healing time between wound treatments with 10% gel and base gel (p < 0.05). Therefore, it can be concluded that the 10% egg white gel is effective in healing cuts in mice as it speeds wound healing and decreases wound size.
format	article
author	Wahyu Widyaningsih Sapto Yuliani Sapto Yuliani Ayu Wulandari Rifka Salsabila
author_facet	Wahyu Widyaningsih Sapto Yuliani Sapto Yuliani Ayu Wulandari Rifka Salsabila
author_sort	Wahyu Widyaningsih
title	Incision wound healing activity of free-range chicken (Gallus domesticus) egg white gel in mice
title_short	Incision wound healing activity of free-range chicken (Gallus domesticus) egg white gel in mice
title_full	Incision wound healing activity of free-range chicken (Gallus domesticus) egg white gel in mice
title_fullStr	Incision wound healing activity of free-range chicken (Gallus domesticus) egg white gel in mice
title_full_unstemmed	Incision wound healing activity of free-range chicken (Gallus domesticus) egg white gel in mice
title_sort	incision wound healing activity of free-range chicken (gallus domesticus) egg white gel in mice
publisher	Universitas Ahmad Dahlan
publishDate	2021
url	https://doaj.org/article/211afe715ad8466b92f45ac98f8ba8aa
work_keys_str_mv	AT wahyuwidyaningsih incisionwoundhealingactivityoffreerangechickengallusdomesticuseggwhitegelinmice AT saptoyuliani incisionwoundhealingactivityoffreerangechickengallusdomesticuseggwhitegelinmice AT saptoyuliani incisionwoundhealingactivityoffreerangechickengallusdomesticuseggwhitegelinmice AT ayuwulandari incisionwoundhealingactivityoffreerangechickengallusdomesticuseggwhitegelinmice AT rifkasalsabila incisionwoundhealingactivityoffreerangechickengallusdomesticuseggwhitegelinmice
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Incision wound healing activity of free-range chicken (Gallus domesticus) egg white gel in mice

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