Dot1 regulates nucleosome dynamics by its inherent histone chaperone activity in yeast

Dot1 is an evolutionarily conserved enzyme, responsible for histone H3K79 methylation in most eukaryotes. Here authors show that, in yeast, Dot1p has histone chaperone activity and regulates nucleosome dynamics via histone exchange in transcribed regions.

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Autores principales:	Soyun Lee, Seunghee Oh, Kwiwan Jeong, Hyelim Jo, Yoonjung Choi, Hogyu David Seo, Minhoo Kim, Joonho Choe, Chang Seob Kwon, Daeyoup Lee
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/212d26a446b048c1a4d3006d7bb52b5b
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spelling	oai:doaj.org-article:212d26a446b048c1a4d3006d7bb52b5b2021-12-02T16:56:39ZDot1 regulates nucleosome dynamics by its inherent histone chaperone activity in yeast10.1038/s41467-017-02759-82041-1723https://doaj.org/article/212d26a446b048c1a4d3006d7bb52b5b2018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02759-8https://doaj.org/toc/2041-1723Dot1 is an evolutionarily conserved enzyme, responsible for histone H3K79 methylation in most eukaryotes. Here authors show that, in yeast, Dot1p has histone chaperone activity and regulates nucleosome dynamics via histone exchange in transcribed regions.Soyun LeeSeunghee OhKwiwan JeongHyelim JoYoonjung ChoiHogyu David SeoMinhoo KimJoonho ChoeChang Seob KwonDaeyoup LeeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Soyun Lee Seunghee Oh Kwiwan Jeong Hyelim Jo Yoonjung Choi Hogyu David Seo Minhoo Kim Joonho Choe Chang Seob Kwon Daeyoup Lee Dot1 regulates nucleosome dynamics by its inherent histone chaperone activity in yeast
description	Dot1 is an evolutionarily conserved enzyme, responsible for histone H3K79 methylation in most eukaryotes. Here authors show that, in yeast, Dot1p has histone chaperone activity and regulates nucleosome dynamics via histone exchange in transcribed regions.
format	article
author	Soyun Lee Seunghee Oh Kwiwan Jeong Hyelim Jo Yoonjung Choi Hogyu David Seo Minhoo Kim Joonho Choe Chang Seob Kwon Daeyoup Lee
author_facet	Soyun Lee Seunghee Oh Kwiwan Jeong Hyelim Jo Yoonjung Choi Hogyu David Seo Minhoo Kim Joonho Choe Chang Seob Kwon Daeyoup Lee
author_sort	Soyun Lee
title	Dot1 regulates nucleosome dynamics by its inherent histone chaperone activity in yeast
title_short	Dot1 regulates nucleosome dynamics by its inherent histone chaperone activity in yeast
title_full	Dot1 regulates nucleosome dynamics by its inherent histone chaperone activity in yeast
title_fullStr	Dot1 regulates nucleosome dynamics by its inherent histone chaperone activity in yeast
title_full_unstemmed	Dot1 regulates nucleosome dynamics by its inherent histone chaperone activity in yeast
title_sort	dot1 regulates nucleosome dynamics by its inherent histone chaperone activity in yeast
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/212d26a446b048c1a4d3006d7bb52b5b
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Dot1 regulates nucleosome dynamics by its inherent histone chaperone activity in yeast

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