Resolving the cause of recurrent Plasmodium vivax malaria probabilistically

Relapse, reinfection and recrudescence can all cause recurrent infection after treatment of Plasmodium vivax malaria in endemic areas, but are difficult to distinguish. Here the authors show that they can be differentiated probabilistically and thereby demonstrate the high efficacy of primaquine tre...

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Autores principales: Aimee R. Taylor, James A. Watson, Cindy S. Chu, Kanokpich Puaprasert, Jureeporn Duanguppama, Nicholas P. J. Day, Francois Nosten, Daniel E. Neafsey, Caroline O. Buckee, Mallika Imwong, Nicholas J. White
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/212ea7b9f9a2421e84355dc5b64bf80d
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spelling oai:doaj.org-article:212ea7b9f9a2421e84355dc5b64bf80d2021-12-02T15:35:47ZResolving the cause of recurrent Plasmodium vivax malaria probabilistically10.1038/s41467-019-13412-x2041-1723https://doaj.org/article/212ea7b9f9a2421e84355dc5b64bf80d2019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13412-xhttps://doaj.org/toc/2041-1723Relapse, reinfection and recrudescence can all cause recurrent infection after treatment of Plasmodium vivax malaria in endemic areas, but are difficult to distinguish. Here the authors show that they can be differentiated probabilistically and thereby demonstrate the high efficacy of primaquine treatment in preventing relapse.Aimee R. TaylorJames A. WatsonCindy S. ChuKanokpich PuaprasertJureeporn DuanguppamaNicholas P. J. DayFrancois NostenDaniel E. NeafseyCaroline O. BuckeeMallika ImwongNicholas J. WhiteNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Aimee R. Taylor
James A. Watson
Cindy S. Chu
Kanokpich Puaprasert
Jureeporn Duanguppama
Nicholas P. J. Day
Francois Nosten
Daniel E. Neafsey
Caroline O. Buckee
Mallika Imwong
Nicholas J. White
Resolving the cause of recurrent Plasmodium vivax malaria probabilistically
description Relapse, reinfection and recrudescence can all cause recurrent infection after treatment of Plasmodium vivax malaria in endemic areas, but are difficult to distinguish. Here the authors show that they can be differentiated probabilistically and thereby demonstrate the high efficacy of primaquine treatment in preventing relapse.
format article
author Aimee R. Taylor
James A. Watson
Cindy S. Chu
Kanokpich Puaprasert
Jureeporn Duanguppama
Nicholas P. J. Day
Francois Nosten
Daniel E. Neafsey
Caroline O. Buckee
Mallika Imwong
Nicholas J. White
author_facet Aimee R. Taylor
James A. Watson
Cindy S. Chu
Kanokpich Puaprasert
Jureeporn Duanguppama
Nicholas P. J. Day
Francois Nosten
Daniel E. Neafsey
Caroline O. Buckee
Mallika Imwong
Nicholas J. White
author_sort Aimee R. Taylor
title Resolving the cause of recurrent Plasmodium vivax malaria probabilistically
title_short Resolving the cause of recurrent Plasmodium vivax malaria probabilistically
title_full Resolving the cause of recurrent Plasmodium vivax malaria probabilistically
title_fullStr Resolving the cause of recurrent Plasmodium vivax malaria probabilistically
title_full_unstemmed Resolving the cause of recurrent Plasmodium vivax malaria probabilistically
title_sort resolving the cause of recurrent plasmodium vivax malaria probabilistically
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/212ea7b9f9a2421e84355dc5b64bf80d
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