Household transmission of influenza A(H1N1)pdm09 in the pandemic and post-pandemic seasons.
<h4>Background</h4>The transmission of influenza viruses occurs person to person and is facilitated by contacts within enclosed environments such as households. The aim of this study was to evaluate secondary attack rates and factors associated with household transmission of laboratory-c...
Guardado en:
| Autores principales: | , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Public Library of Science (PLoS)
2014
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/214228a3182b4a9492f51555823fc774 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:214228a3182b4a9492f51555823fc774 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:214228a3182b4a9492f51555823fc7742021-11-25T05:59:22ZHousehold transmission of influenza A(H1N1)pdm09 in the pandemic and post-pandemic seasons.1932-620310.1371/journal.pone.0108485https://doaj.org/article/214228a3182b4a9492f51555823fc7742014-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0108485https://doaj.org/toc/1932-6203<h4>Background</h4>The transmission of influenza viruses occurs person to person and is facilitated by contacts within enclosed environments such as households. The aim of this study was to evaluate secondary attack rates and factors associated with household transmission of laboratory-confirmed influenza A(H1N1)pdm09 in the pandemic and post-pandemic seasons.<h4>Methods</h4>During the 2009-2010 and 2010-2011 influenza seasons, 76 sentinel physicians in Navarra, Spain, took nasopharyngeal and pharyngeal swabs from patients diagnosed with influenza-like illness. A trained nurse telephoned households of those patients who were laboratory-confirmed for influenza A(H1N1)pdm09 to ask about the symptoms, risk factors and vaccination status of each household member.<h4>Results</h4>In the 405 households with a patient laboratory-confirmed for influenza A(H1N1)pdm09, 977 susceptible contacts were identified; 16% of them (95% CI 14-19%) presented influenza-like illness and were considered as secondary cases. The secondary attack rate was 14% in 2009-2010 and 19% in the 2010-2011 season (p=0.049), an increase that mainly affected persons with major chronic conditions. In the multivariate logistic regression analysis, the risk of being a secondary case was higher in the 2010-2011 season than in the 2009-2010 season (adjusted odds ratio: 1.72; 95% CI 1.17-2.54), and in children under 5 years, with a decreasing risk in older contacts. Influenza vaccination was associated with lesser incidence of influenza-like illness near to statistical significance (adjusted odds ratio: 0.29; 95% CI 0.08-1.03).<h4>Conclusion</h4>The secondary attack rate in households was higher in the second season than in the first pandemic season. Children had a greater risk of infection. Preventive measures should be maintained in the second pandemic season, especially in high-risk persons.Itziar CasadoIván Martínez-BazRosana BurguiFátima IrisarriMaite ArriazuFernando ElíaAna NavascuésCarmen EzpeletaPablo AldazJesús CastillaPrimary Health Care Sentinel Network of NavarraPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 9, Iss 9, p e108485 (2014) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Medicine R Science Q |
| spellingShingle |
Medicine R Science Q Itziar Casado Iván Martínez-Baz Rosana Burgui Fátima Irisarri Maite Arriazu Fernando Elía Ana Navascués Carmen Ezpeleta Pablo Aldaz Jesús Castilla Primary Health Care Sentinel Network of Navarra Household transmission of influenza A(H1N1)pdm09 in the pandemic and post-pandemic seasons. |
| description |
<h4>Background</h4>The transmission of influenza viruses occurs person to person and is facilitated by contacts within enclosed environments such as households. The aim of this study was to evaluate secondary attack rates and factors associated with household transmission of laboratory-confirmed influenza A(H1N1)pdm09 in the pandemic and post-pandemic seasons.<h4>Methods</h4>During the 2009-2010 and 2010-2011 influenza seasons, 76 sentinel physicians in Navarra, Spain, took nasopharyngeal and pharyngeal swabs from patients diagnosed with influenza-like illness. A trained nurse telephoned households of those patients who were laboratory-confirmed for influenza A(H1N1)pdm09 to ask about the symptoms, risk factors and vaccination status of each household member.<h4>Results</h4>In the 405 households with a patient laboratory-confirmed for influenza A(H1N1)pdm09, 977 susceptible contacts were identified; 16% of them (95% CI 14-19%) presented influenza-like illness and were considered as secondary cases. The secondary attack rate was 14% in 2009-2010 and 19% in the 2010-2011 season (p=0.049), an increase that mainly affected persons with major chronic conditions. In the multivariate logistic regression analysis, the risk of being a secondary case was higher in the 2010-2011 season than in the 2009-2010 season (adjusted odds ratio: 1.72; 95% CI 1.17-2.54), and in children under 5 years, with a decreasing risk in older contacts. Influenza vaccination was associated with lesser incidence of influenza-like illness near to statistical significance (adjusted odds ratio: 0.29; 95% CI 0.08-1.03).<h4>Conclusion</h4>The secondary attack rate in households was higher in the second season than in the first pandemic season. Children had a greater risk of infection. Preventive measures should be maintained in the second pandemic season, especially in high-risk persons. |
| format |
article |
| author |
Itziar Casado Iván Martínez-Baz Rosana Burgui Fátima Irisarri Maite Arriazu Fernando Elía Ana Navascués Carmen Ezpeleta Pablo Aldaz Jesús Castilla Primary Health Care Sentinel Network of Navarra |
| author_facet |
Itziar Casado Iván Martínez-Baz Rosana Burgui Fátima Irisarri Maite Arriazu Fernando Elía Ana Navascués Carmen Ezpeleta Pablo Aldaz Jesús Castilla Primary Health Care Sentinel Network of Navarra |
| author_sort |
Itziar Casado |
| title |
Household transmission of influenza A(H1N1)pdm09 in the pandemic and post-pandemic seasons. |
| title_short |
Household transmission of influenza A(H1N1)pdm09 in the pandemic and post-pandemic seasons. |
| title_full |
Household transmission of influenza A(H1N1)pdm09 in the pandemic and post-pandemic seasons. |
| title_fullStr |
Household transmission of influenza A(H1N1)pdm09 in the pandemic and post-pandemic seasons. |
| title_full_unstemmed |
Household transmission of influenza A(H1N1)pdm09 in the pandemic and post-pandemic seasons. |
| title_sort |
household transmission of influenza a(h1n1)pdm09 in the pandemic and post-pandemic seasons. |
| publisher |
Public Library of Science (PLoS) |
| publishDate |
2014 |
| url |
https://doaj.org/article/214228a3182b4a9492f51555823fc774 |
| work_keys_str_mv |
AT itziarcasado householdtransmissionofinfluenzaah1n1pdm09inthepandemicandpostpandemicseasons AT ivanmartinezbaz householdtransmissionofinfluenzaah1n1pdm09inthepandemicandpostpandemicseasons AT rosanaburgui householdtransmissionofinfluenzaah1n1pdm09inthepandemicandpostpandemicseasons AT fatimairisarri householdtransmissionofinfluenzaah1n1pdm09inthepandemicandpostpandemicseasons AT maitearriazu householdtransmissionofinfluenzaah1n1pdm09inthepandemicandpostpandemicseasons AT fernandoelia householdtransmissionofinfluenzaah1n1pdm09inthepandemicandpostpandemicseasons AT ananavascues householdtransmissionofinfluenzaah1n1pdm09inthepandemicandpostpandemicseasons AT carmenezpeleta householdtransmissionofinfluenzaah1n1pdm09inthepandemicandpostpandemicseasons AT pabloaldaz householdtransmissionofinfluenzaah1n1pdm09inthepandemicandpostpandemicseasons AT jesuscastilla householdtransmissionofinfluenzaah1n1pdm09inthepandemicandpostpandemicseasons AT primaryhealthcaresentinelnetworkofnavarra householdtransmissionofinfluenzaah1n1pdm09inthepandemicandpostpandemicseasons |
| _version_ |
1718414267357593600 |