Trpm5 channels encode bistability of spinal motoneurons and ensure motor control of hindlimbs in mice
The authors show that Trpm5, but not Trpm4, is the main Na+ -permeant channel mediating the warmth-activated ICaN in lumbar motoneurons. Trpm5 is also critical in generating plateau potentials in bistable motoneurons that are essential for producing a postural tone in hindlimbs and amplifying the lo...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2021
|
| Subjects: | |
| Online Access: | https://doaj.org/article/214612d1787d4019a823b0b8efb12a75 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|