Diphtheria in an Adult: A Paradigm of Waning Immunity

In the past 10 years, there have been several reported cases of the existence of a vaccine-preventable disease from several Indian states. Diphtheria, re-emerge as a major public health problem as this fatal infection used to be noticed in toddlers and school-going has now been stated to occur amo...

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Autores principales:	Lipika Singhal, Ivneet Kour, Varsha Gupta, Surinder Singhal
Formato:	article
Lenguaje:	EN
Publicado:	JCDR Research and Publications Private Limited 2021
Materias:	adult diphtheria pseudomembrane vaccine preventable infection Medicine R
Acceso en línea:	https://doaj.org/article/21483ea7ab2e4527ae44c29b2a54c4ed
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spelling	oai:doaj.org-article:21483ea7ab2e4527ae44c29b2a54c4ed2021-11-07T09:34:43ZDiphtheria in an Adult: A Paradigm of Waning Immunity10.7860/JCDR/2021/49665.154090973-709X2249-782Xhttps://doaj.org/article/21483ea7ab2e4527ae44c29b2a54c4ed2021-09-01T00:00:00Zhttps://www.jcdr.net/articles/PDF/15409/49665_CE[Ra1]_F[SH]_PF1(AG_SHU)_PFA(AG_KM)_PN(KM).pdfhttps://doaj.org/toc/0973-709Xhttps://doaj.org/toc/2249-782XIn the past 10 years, there have been several reported cases of the existence of a vaccine-preventable disease from several Indian states. Diphtheria, re-emerge as a major public health problem as this fatal infection used to be noticed in toddlers and school-going has now been stated to occur amongst adults also despite the fully functional Universal Immunisation Program (UIP) in India. India contributed about 53.9% of diphtheria cases globally in the year 2016. In cases, the reason for the upsurge could be attributed to lack of proper immunisation or waning of vaccine-induced immunity with increasing age. Here, a case of a 24-year-old adult male was reported who presented with acute membranous tonsillitis, a preliminary diagnosis made on physical examination. Corynaebacterium diphtheriae was isolated. Finally, the isolate was confirmed as C. diphtheriae using Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectrometry (MALDI-TOF MS) system.Lipika SinghalIvneet KourVarsha GuptaSurinder SinghalJCDR Research and Publications Private Limitedarticleadult diphtheriapseudomembranevaccine preventable infectionMedicineRENJournal of Clinical and Diagnostic Research, Vol 15, Iss 9, Pp DD01-DD03 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	adult diphtheria pseudomembrane vaccine preventable infection Medicine R
spellingShingle	adult diphtheria pseudomembrane vaccine preventable infection Medicine R Lipika Singhal Ivneet Kour Varsha Gupta Surinder Singhal Diphtheria in an Adult: A Paradigm of Waning Immunity
description	In the past 10 years, there have been several reported cases of the existence of a vaccine-preventable disease from several Indian states. Diphtheria, re-emerge as a major public health problem as this fatal infection used to be noticed in toddlers and school-going has now been stated to occur amongst adults also despite the fully functional Universal Immunisation Program (UIP) in India. India contributed about 53.9% of diphtheria cases globally in the year 2016. In cases, the reason for the upsurge could be attributed to lack of proper immunisation or waning of vaccine-induced immunity with increasing age. Here, a case of a 24-year-old adult male was reported who presented with acute membranous tonsillitis, a preliminary diagnosis made on physical examination. Corynaebacterium diphtheriae was isolated. Finally, the isolate was confirmed as C. diphtheriae using Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectrometry (MALDI-TOF MS) system.
format	article
author	Lipika Singhal Ivneet Kour Varsha Gupta Surinder Singhal
author_facet	Lipika Singhal Ivneet Kour Varsha Gupta Surinder Singhal
author_sort	Lipika Singhal
title	Diphtheria in an Adult: A Paradigm of Waning Immunity
title_short	Diphtheria in an Adult: A Paradigm of Waning Immunity
title_full	Diphtheria in an Adult: A Paradigm of Waning Immunity
title_fullStr	Diphtheria in an Adult: A Paradigm of Waning Immunity
title_full_unstemmed	Diphtheria in an Adult: A Paradigm of Waning Immunity
title_sort	diphtheria in an adult: a paradigm of waning immunity
publisher	JCDR Research and Publications Private Limited
publishDate	2021
url	https://doaj.org/article/21483ea7ab2e4527ae44c29b2a54c4ed
work_keys_str_mv	AT lipikasinghal diphtheriainanadultaparadigmofwaningimmunity AT ivneetkour diphtheriainanadultaparadigmofwaningimmunity AT varshagupta diphtheriainanadultaparadigmofwaningimmunity AT surindersinghal diphtheriainanadultaparadigmofwaningimmunity
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Diphtheria in an Adult: A Paradigm of Waning Immunity

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