DOES AUTO TRANSFUSION OF UNPROCESSED RESIDUAL BLOOD IN THE CARDIOPULMONARY BYPASS CIRCUIT LEAD TO UNFAVORABLE OUTCOMES?

Objective: Transfusion of residual blood left in the cardiopulmonary bypass circuit is recommended. Whether this blood should be processed or not before transfusion is not known. Study Design: A prospective non-randomized case control study. Place and Duration of Study: A tertiary care heart c...

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Autores principales:	Musfireh Siddiqeh, Imran Khan, Ali Gohar Zamir, Asif Mehmood Janjua, Beenish Munir, Qudsia Anjum
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2020
Materias:	cardiopulmonary bypass residual blood re-transfusion Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/214c16cdad9e423db0bad75dc9b28016
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spelling	oai:doaj.org-article:214c16cdad9e423db0bad75dc9b280162021-12-02T19:11:33ZDOES AUTO TRANSFUSION OF UNPROCESSED RESIDUAL BLOOD IN THE CARDIOPULMONARY BYPASS CIRCUIT LEAD TO UNFAVORABLE OUTCOMES?doi.org/10.51253/pafmj.v70iSuppl-4.60310030-96482411-8842https://doaj.org/article/214c16cdad9e423db0bad75dc9b280162020-12-01T00:00:00Zhttps://pafmj.org/index.php/PAFMJ/article/view/6031https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: Transfusion of residual blood left in the cardiopulmonary bypass circuit is recommended. Whether this blood should be processed or not before transfusion is not known. Study Design: A prospective non-randomized case control study. Place and Duration of Study: A tertiary care heart center, from Jan 2016 to Dec 2018. Methodology: A prospective non-randomized case control study was designed. Consecutive patients operated at a tertiary care hospital were included in the study who underwent different open-heart procedures on cardiopulmonary bypass. Patients were divided into two groups. Those who received the unprocessed residual blood transfusion, residual volume retransfused at the end of cardiopulmonary bypass and those who did not, residual volume not retransfused (RVNR). Important perioperative data was collected from the hospital database and analyzed using IBM SPSS-statistics 23.0 (IBM, SPSS Inc., Chicago, IL). Results: Of the 120 patients, 56 patients were included in the RVR group and 64 in the RVNR group. Mean age in the RVR group was 49.41 ± 14.38 years and in the RVNR group 49.27 ± 16.36 years (p=0.96). Female patients were 9 (16.07%) in the RVR group and 20 (31.25%) in the RVNR group. Residual blood left in the circuit was 271.43 ± 52 ml in the RVR group and 264.06 ± 54.5 ml in the RVNR group (p=0.45). Hemoglobin measured in ICU was 10.5 ± 1.12 gm/dl in the RVR group and 9.97 ± 1.25 gm/dl in the RVNR group (0.02). Blood products were needed in 27 patients in RVR group and 21 patients in RVNR group (p=0.57). There was no significant difference between the two groups with respect to total drainage in the first 24 hours (p=0.89). Similarly, the re-exploration rates were not different between the two groups (p=0.50). Conclusion: Re-transfusion of residual blood left in the CPB circuit is a safe practiced. If this blood is transfused in an unprocessed form, it does not lead to adverse outcomes.Musfireh SiddiqehImran KhanAli Gohar ZamirAsif Mehmood JanjuaBeenish MunirQudsia AnjumArmy Medical College Rawalpindiarticlecardiopulmonary bypassresidual blood re-transfusionMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 70, Iss 4, Pp 819-823 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	cardiopulmonary bypass residual blood re-transfusion Medicine R Medicine (General) R5-920
spellingShingle	cardiopulmonary bypass residual blood re-transfusion Medicine R Medicine (General) R5-920 Musfireh Siddiqeh Imran Khan Ali Gohar Zamir Asif Mehmood Janjua Beenish Munir Qudsia Anjum DOES AUTO TRANSFUSION OF UNPROCESSED RESIDUAL BLOOD IN THE CARDIOPULMONARY BYPASS CIRCUIT LEAD TO UNFAVORABLE OUTCOMES?
description	Objective: Transfusion of residual blood left in the cardiopulmonary bypass circuit is recommended. Whether this blood should be processed or not before transfusion is not known. Study Design: A prospective non-randomized case control study. Place and Duration of Study: A tertiary care heart center, from Jan 2016 to Dec 2018. Methodology: A prospective non-randomized case control study was designed. Consecutive patients operated at a tertiary care hospital were included in the study who underwent different open-heart procedures on cardiopulmonary bypass. Patients were divided into two groups. Those who received the unprocessed residual blood transfusion, residual volume retransfused at the end of cardiopulmonary bypass and those who did not, residual volume not retransfused (RVNR). Important perioperative data was collected from the hospital database and analyzed using IBM SPSS-statistics 23.0 (IBM, SPSS Inc., Chicago, IL). Results: Of the 120 patients, 56 patients were included in the RVR group and 64 in the RVNR group. Mean age in the RVR group was 49.41 ± 14.38 years and in the RVNR group 49.27 ± 16.36 years (p=0.96). Female patients were 9 (16.07%) in the RVR group and 20 (31.25%) in the RVNR group. Residual blood left in the circuit was 271.43 ± 52 ml in the RVR group and 264.06 ± 54.5 ml in the RVNR group (p=0.45). Hemoglobin measured in ICU was 10.5 ± 1.12 gm/dl in the RVR group and 9.97 ± 1.25 gm/dl in the RVNR group (0.02). Blood products were needed in 27 patients in RVR group and 21 patients in RVNR group (p=0.57). There was no significant difference between the two groups with respect to total drainage in the first 24 hours (p=0.89). Similarly, the re-exploration rates were not different between the two groups (p=0.50). Conclusion: Re-transfusion of residual blood left in the CPB circuit is a safe practiced. If this blood is transfused in an unprocessed form, it does not lead to adverse outcomes.
format	article
author	Musfireh Siddiqeh Imran Khan Ali Gohar Zamir Asif Mehmood Janjua Beenish Munir Qudsia Anjum
author_facet	Musfireh Siddiqeh Imran Khan Ali Gohar Zamir Asif Mehmood Janjua Beenish Munir Qudsia Anjum
author_sort	Musfireh Siddiqeh
title	DOES AUTO TRANSFUSION OF UNPROCESSED RESIDUAL BLOOD IN THE CARDIOPULMONARY BYPASS CIRCUIT LEAD TO UNFAVORABLE OUTCOMES?
title_short	DOES AUTO TRANSFUSION OF UNPROCESSED RESIDUAL BLOOD IN THE CARDIOPULMONARY BYPASS CIRCUIT LEAD TO UNFAVORABLE OUTCOMES?
title_full	DOES AUTO TRANSFUSION OF UNPROCESSED RESIDUAL BLOOD IN THE CARDIOPULMONARY BYPASS CIRCUIT LEAD TO UNFAVORABLE OUTCOMES?
title_fullStr	DOES AUTO TRANSFUSION OF UNPROCESSED RESIDUAL BLOOD IN THE CARDIOPULMONARY BYPASS CIRCUIT LEAD TO UNFAVORABLE OUTCOMES?
title_full_unstemmed	DOES AUTO TRANSFUSION OF UNPROCESSED RESIDUAL BLOOD IN THE CARDIOPULMONARY BYPASS CIRCUIT LEAD TO UNFAVORABLE OUTCOMES?
title_sort	does auto transfusion of unprocessed residual blood in the cardiopulmonary bypass circuit lead to unfavorable outcomes?
publisher	Army Medical College Rawalpindi
publishDate	2020
url	https://doaj.org/article/214c16cdad9e423db0bad75dc9b28016
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DOES AUTO TRANSFUSION OF UNPROCESSED RESIDUAL BLOOD IN THE CARDIOPULMONARY BYPASS CIRCUIT LEAD TO UNFAVORABLE OUTCOMES?

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