Protein-protein interactions and metabolite channelling in the plant tricarboxylic acid cycle

A metabolon is a complex of sequential metabolic enzymes that channels substrates directly between enzymes, thus optimizing metabolic flux. Here Zhanget al. provide protein interaction and isotope dilution data that support the existence of a metabolon that channels both citrate and fumarate in the...

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Autores principales: Youjun Zhang, Katherine F. M. Beard, Corné Swart, Susan Bergmann, Ina Krahnert, Zoran Nikoloski, Alexander Graf, R. George Ratcliffe, Lee J. Sweetlove, Alisdair R. Fernie, Toshihiro Obata
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/214c6f462dcf4784a3f060e96f7707b0
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Sumario:A metabolon is a complex of sequential metabolic enzymes that channels substrates directly between enzymes, thus optimizing metabolic flux. Here Zhanget al. provide protein interaction and isotope dilution data that support the existence of a metabolon that channels both citrate and fumarate in the plant TCA cycle.