A Comparison of Clinical Findings and Laboratory Test Results Between Hospitalized Children with COVID-19 and Influenza

Aim:It can be challenging to distinguish between influenza and coronavirus disease-2019 (COVID-19) during the influenza season. Therefore, we aimed to compare the clinical symptoms, laboratory findings, and outcomes of these two diseases in children.Materials and Methods:Thirty-two children with COV...

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Autores principales: Gülşen Akkoç, Ayşe Ağbaş, Nilgün Selçuk Duru
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TR
Publicado: Galenos Yayinevi 2021
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Acceso en línea:https://doaj.org/article/214e53f1338341cfa410e625a23d6f5b
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spelling oai:doaj.org-article:214e53f1338341cfa410e625a23d6f5b2021-11-11T11:27:23ZA Comparison of Clinical Findings and Laboratory Test Results Between Hospitalized Children with COVID-19 and Influenza2147-94452587-247810.4274/jpr.galenos.2021.48751https://doaj.org/article/214e53f1338341cfa410e625a23d6f5b2021-12-01T00:00:00Z http://jpedres.org/archives/archive-detail/article-preview/a-comparison-of-clinical-findings-and-laboratory-t/49639 https://doaj.org/toc/2147-9445https://doaj.org/toc/2587-2478Aim:It can be challenging to distinguish between influenza and coronavirus disease-2019 (COVID-19) during the influenza season. Therefore, we aimed to compare the clinical symptoms, laboratory findings, and outcomes of these two diseases in children.Materials and Methods:Thirty-two children with COVID-19 and 22 children with influenza who were hospitalized in our clinic were included in this study. The demographic, clinical, and laboratory findings of these patients were retrospectively reviewed.Results:The median age of patients with influenza and COVID-19 was 1.4 and 15.3 years, respectively. Fever (77.3% vs 46.9%, p=0.02), nasal obstruction (27.3% vs 0%, p=0.003), wheezing (54.5% vs 3.1%, p<0.001), bilateral crackling sounds (63.6% vs 15.6%, p<0.001), prolonged expirium (63.6% vs 3.1%, p<0.001), tachycardia (36.4% vs 0%, p<0.001) and tachypnea (54.5% vs 0%, p<0.001) were significantly more frequent in those patients with influenza compared to COVID-19. Patients with influenza had significantly increased leucocyte count, lymphocyte count, and aminotransferase levels and lower albumin levels compared to those patients with COVID-19. In the influenza group, three patients needed intensive care, and one of them died. None of the patients with COVID-19 needed intensive care and there was no death in this group.Conclusion:In hospitalized children, the clinical and laboratory findings were milder in those patients with COVID-19 compared to influenza.Gülşen AkkoçAyşe AğbaşNilgün Selçuk DuruGalenos Yayineviarticlechildrencoronaviruscovid-19influenzaMedicineRPediatricsRJ1-570ENTRJournal of Pediatric Research, Vol 8, Iss 4, Pp 432-437 (2021)
institution DOAJ
collection DOAJ
language EN
TR
topic children
coronavirus
covid-19
influenza
Medicine
R
Pediatrics
RJ1-570
spellingShingle children
coronavirus
covid-19
influenza
Medicine
R
Pediatrics
RJ1-570
Gülşen Akkoç
Ayşe Ağbaş
Nilgün Selçuk Duru
A Comparison of Clinical Findings and Laboratory Test Results Between Hospitalized Children with COVID-19 and Influenza
description Aim:It can be challenging to distinguish between influenza and coronavirus disease-2019 (COVID-19) during the influenza season. Therefore, we aimed to compare the clinical symptoms, laboratory findings, and outcomes of these two diseases in children.Materials and Methods:Thirty-two children with COVID-19 and 22 children with influenza who were hospitalized in our clinic were included in this study. The demographic, clinical, and laboratory findings of these patients were retrospectively reviewed.Results:The median age of patients with influenza and COVID-19 was 1.4 and 15.3 years, respectively. Fever (77.3% vs 46.9%, p=0.02), nasal obstruction (27.3% vs 0%, p=0.003), wheezing (54.5% vs 3.1%, p<0.001), bilateral crackling sounds (63.6% vs 15.6%, p<0.001), prolonged expirium (63.6% vs 3.1%, p<0.001), tachycardia (36.4% vs 0%, p<0.001) and tachypnea (54.5% vs 0%, p<0.001) were significantly more frequent in those patients with influenza compared to COVID-19. Patients with influenza had significantly increased leucocyte count, lymphocyte count, and aminotransferase levels and lower albumin levels compared to those patients with COVID-19. In the influenza group, three patients needed intensive care, and one of them died. None of the patients with COVID-19 needed intensive care and there was no death in this group.Conclusion:In hospitalized children, the clinical and laboratory findings were milder in those patients with COVID-19 compared to influenza.
format article
author Gülşen Akkoç
Ayşe Ağbaş
Nilgün Selçuk Duru
author_facet Gülşen Akkoç
Ayşe Ağbaş
Nilgün Selçuk Duru
author_sort Gülşen Akkoç
title A Comparison of Clinical Findings and Laboratory Test Results Between Hospitalized Children with COVID-19 and Influenza
title_short A Comparison of Clinical Findings and Laboratory Test Results Between Hospitalized Children with COVID-19 and Influenza
title_full A Comparison of Clinical Findings and Laboratory Test Results Between Hospitalized Children with COVID-19 and Influenza
title_fullStr A Comparison of Clinical Findings and Laboratory Test Results Between Hospitalized Children with COVID-19 and Influenza
title_full_unstemmed A Comparison of Clinical Findings and Laboratory Test Results Between Hospitalized Children with COVID-19 and Influenza
title_sort comparison of clinical findings and laboratory test results between hospitalized children with covid-19 and influenza
publisher Galenos Yayinevi
publishDate 2021
url https://doaj.org/article/214e53f1338341cfa410e625a23d6f5b
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