The Role of Oxidative Stress in Sarcoidosis

Sarcoidosis is a rare, systemic inflammatory disease whose diagnosis and management can pose a challenge for clinicians and specialists. Scientific knowledge on the molecular pathways that drive its development is still lacking, with no standardized therapies available and insufficient strategies to...

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Autores principales:	Sara Solveig Fois, Sara Canu, Alessandro Giuseppe Fois
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	sarcoidosis oxidative stress antioxidant biomarker Biology (General) QH301-705.5 Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/214e9c3a0dc8445d95f1223d7556cfa9
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id	oai:doaj.org-article:214e9c3a0dc8445d95f1223d7556cfa9
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spelling	oai:doaj.org-article:214e9c3a0dc8445d95f1223d7556cfa92021-11-11T17:10:17ZThe Role of Oxidative Stress in Sarcoidosis10.3390/ijms2221117121422-00671661-6596https://doaj.org/article/214e9c3a0dc8445d95f1223d7556cfa92021-10-01T00:00:00Zhttps://www.mdpi.com/1422-0067/22/21/11712https://doaj.org/toc/1661-6596https://doaj.org/toc/1422-0067Sarcoidosis is a rare, systemic inflammatory disease whose diagnosis and management can pose a challenge for clinicians and specialists. Scientific knowledge on the molecular pathways that drive its development is still lacking, with no standardized therapies available and insufficient strategies to predict patient outcome. In recent years, oxidative stress has been highlighted as an important factor in the pathogenesis of sarcoidosis, involving several enzymes and molecules in the mechanism of the disease. This review presents current data on the role of oxidative stress in sarcoidosis and its interaction with inflammation, as well as the application of antioxidative therapy in the disease.Sara Solveig FoisSara CanuAlessandro Giuseppe FoisMDPI AGarticlesarcoidosisoxidative stressantioxidantbiomarkerBiology (General)QH301-705.5ChemistryQD1-999ENInternational Journal of Molecular Sciences, Vol 22, Iss 11712, p 11712 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	sarcoidosis oxidative stress antioxidant biomarker Biology (General) QH301-705.5 Chemistry QD1-999
spellingShingle	sarcoidosis oxidative stress antioxidant biomarker Biology (General) QH301-705.5 Chemistry QD1-999 Sara Solveig Fois Sara Canu Alessandro Giuseppe Fois The Role of Oxidative Stress in Sarcoidosis
description	Sarcoidosis is a rare, systemic inflammatory disease whose diagnosis and management can pose a challenge for clinicians and specialists. Scientific knowledge on the molecular pathways that drive its development is still lacking, with no standardized therapies available and insufficient strategies to predict patient outcome. In recent years, oxidative stress has been highlighted as an important factor in the pathogenesis of sarcoidosis, involving several enzymes and molecules in the mechanism of the disease. This review presents current data on the role of oxidative stress in sarcoidosis and its interaction with inflammation, as well as the application of antioxidative therapy in the disease.
format	article
author	Sara Solveig Fois Sara Canu Alessandro Giuseppe Fois
author_facet	Sara Solveig Fois Sara Canu Alessandro Giuseppe Fois
author_sort	Sara Solveig Fois
title	The Role of Oxidative Stress in Sarcoidosis
title_short	The Role of Oxidative Stress in Sarcoidosis
title_full	The Role of Oxidative Stress in Sarcoidosis
title_fullStr	The Role of Oxidative Stress in Sarcoidosis
title_full_unstemmed	The Role of Oxidative Stress in Sarcoidosis
title_sort	role of oxidative stress in sarcoidosis
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/214e9c3a0dc8445d95f1223d7556cfa9
work_keys_str_mv	AT sarasolveigfois theroleofoxidativestressinsarcoidosis AT saracanu theroleofoxidativestressinsarcoidosis AT alessandrogiuseppefois theroleofoxidativestressinsarcoidosis AT sarasolveigfois roleofoxidativestressinsarcoidosis AT saracanu roleofoxidativestressinsarcoidosis AT alessandrogiuseppefois roleofoxidativestressinsarcoidosis
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The Role of Oxidative Stress in Sarcoidosis

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