PLA2R binds to the annexin A2-S100A10 complex in human podocytes

PLA2R binds to the annexin A2-S100A10 complex in human podocytes

Abstract Phospholipase A2 receptor (PLA2R) is a member of the mannose receptor family found in podocytes in human kidney. PLA2R is the target of the autoimmune disease, membranous nephropathy, characterised by production of anti-PLA2R autoantibodies which bind to the podocyte. However the function o...

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Autores principales: Maryline Fresquet, Thomas A. Jowitt, Edward A. McKenzie, Matthew D. Ball, Michael J. Randles, Rachel Lennon, Paul E. Brenchley
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/2153c86a3e0c4f218eab15f2eb4b83f0
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