Network medicine for disease module identification and drug repurposing with the NeDRex platform

There is an unmet need for adaptable tools allowing biomedical researchers to employ network-based drug repurposing approaches for their individual use cases. Here, the authors close this gap with NeDRex, an integrative and interactive platform.

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Autores principales: Sepideh Sadegh, James Skelton, Elisa Anastasi, Judith Bernett, David B. Blumenthal, Gihanna Galindez, Marisol Salgado-Albarrán, Olga Lazareva, Keith Flanagan, Simon Cockell, Cristian Nogales, Ana I. Casas, Harald H. H. W. Schmidt, Jan Baumbach, Anil Wipat, Tim Kacprowski
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/215680eb37af47198ac9250590ddadb5
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spelling oai:doaj.org-article:215680eb37af47198ac9250590ddadb52021-11-28T12:32:41ZNetwork medicine for disease module identification and drug repurposing with the NeDRex platform10.1038/s41467-021-27138-22041-1723https://doaj.org/article/215680eb37af47198ac9250590ddadb52021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-27138-2https://doaj.org/toc/2041-1723There is an unmet need for adaptable tools allowing biomedical researchers to employ network-based drug repurposing approaches for their individual use cases. Here, the authors close this gap with NeDRex, an integrative and interactive platform.Sepideh SadeghJames SkeltonElisa AnastasiJudith BernettDavid B. BlumenthalGihanna GalindezMarisol Salgado-AlbarránOlga LazarevaKeith FlanaganSimon CockellCristian NogalesAna I. CasasHarald H. H. W. SchmidtJan BaumbachAnil WipatTim KacprowskiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sepideh Sadegh
James Skelton
Elisa Anastasi
Judith Bernett
David B. Blumenthal
Gihanna Galindez
Marisol Salgado-Albarrán
Olga Lazareva
Keith Flanagan
Simon Cockell
Cristian Nogales
Ana I. Casas
Harald H. H. W. Schmidt
Jan Baumbach
Anil Wipat
Tim Kacprowski
Network medicine for disease module identification and drug repurposing with the NeDRex platform
description There is an unmet need for adaptable tools allowing biomedical researchers to employ network-based drug repurposing approaches for their individual use cases. Here, the authors close this gap with NeDRex, an integrative and interactive platform.
format article
author Sepideh Sadegh
James Skelton
Elisa Anastasi
Judith Bernett
David B. Blumenthal
Gihanna Galindez
Marisol Salgado-Albarrán
Olga Lazareva
Keith Flanagan
Simon Cockell
Cristian Nogales
Ana I. Casas
Harald H. H. W. Schmidt
Jan Baumbach
Anil Wipat
Tim Kacprowski
author_facet Sepideh Sadegh
James Skelton
Elisa Anastasi
Judith Bernett
David B. Blumenthal
Gihanna Galindez
Marisol Salgado-Albarrán
Olga Lazareva
Keith Flanagan
Simon Cockell
Cristian Nogales
Ana I. Casas
Harald H. H. W. Schmidt
Jan Baumbach
Anil Wipat
Tim Kacprowski
author_sort Sepideh Sadegh
title Network medicine for disease module identification and drug repurposing with the NeDRex platform
title_short Network medicine for disease module identification and drug repurposing with the NeDRex platform
title_full Network medicine for disease module identification and drug repurposing with the NeDRex platform
title_fullStr Network medicine for disease module identification and drug repurposing with the NeDRex platform
title_full_unstemmed Network medicine for disease module identification and drug repurposing with the NeDRex platform
title_sort network medicine for disease module identification and drug repurposing with the nedrex platform
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/215680eb37af47198ac9250590ddadb5
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