Differential whole-genome doubling and homologous recombination deficiencies across breast cancer subtypes from the Taiwanese population

Wu, Hsieh et al. analyze Taiwanese breast cancer patient samples using whole-exome sequencing to examine the heterogeneity and homogeneity in the timing and dependencies of somatic aberrations across disease subtypes. The authors focus on somatic alterations and related features that correlate with...

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Autores principales: Chia-Hsin Wu, Chia-Shan Hsieh, Yo-Cheng Chang, Chi-Cheng Huang, Hsien-Tang Yeh, Ming-Feng Hou, Yuan-Chiang Chung, Shih-Hsin Tu, King-Jen Chang, Amrita Chattopadhyay, Liang-Chuan Lai, Tzu-Pin Lu, Yung-Hua Li, Mong-Hsun Tsai, Eric Y. Chuang
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/21619eb086eb4dc1b61fe904c1ac2806
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spelling oai:doaj.org-article:21619eb086eb4dc1b61fe904c1ac28062021-12-02T17:19:12ZDifferential whole-genome doubling and homologous recombination deficiencies across breast cancer subtypes from the Taiwanese population10.1038/s42003-021-02597-x2399-3642https://doaj.org/article/21619eb086eb4dc1b61fe904c1ac28062021-09-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02597-xhttps://doaj.org/toc/2399-3642Wu, Hsieh et al. analyze Taiwanese breast cancer patient samples using whole-exome sequencing to examine the heterogeneity and homogeneity in the timing and dependencies of somatic aberrations across disease subtypes. The authors focus on somatic alterations and related features that correlate with whole genome doubling, including homologous recombination deficiencies.Chia-Hsin WuChia-Shan HsiehYo-Cheng ChangChi-Cheng HuangHsien-Tang YehMing-Feng HouYuan-Chiang ChungShih-Hsin TuKing-Jen ChangAmrita ChattopadhyayLiang-Chuan LaiTzu-Pin LuYung-Hua LiMong-Hsun TsaiEric Y. ChuangNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Chia-Hsin Wu
Chia-Shan Hsieh
Yo-Cheng Chang
Chi-Cheng Huang
Hsien-Tang Yeh
Ming-Feng Hou
Yuan-Chiang Chung
Shih-Hsin Tu
King-Jen Chang
Amrita Chattopadhyay
Liang-Chuan Lai
Tzu-Pin Lu
Yung-Hua Li
Mong-Hsun Tsai
Eric Y. Chuang
Differential whole-genome doubling and homologous recombination deficiencies across breast cancer subtypes from the Taiwanese population
description Wu, Hsieh et al. analyze Taiwanese breast cancer patient samples using whole-exome sequencing to examine the heterogeneity and homogeneity in the timing and dependencies of somatic aberrations across disease subtypes. The authors focus on somatic alterations and related features that correlate with whole genome doubling, including homologous recombination deficiencies.
format article
author Chia-Hsin Wu
Chia-Shan Hsieh
Yo-Cheng Chang
Chi-Cheng Huang
Hsien-Tang Yeh
Ming-Feng Hou
Yuan-Chiang Chung
Shih-Hsin Tu
King-Jen Chang
Amrita Chattopadhyay
Liang-Chuan Lai
Tzu-Pin Lu
Yung-Hua Li
Mong-Hsun Tsai
Eric Y. Chuang
author_facet Chia-Hsin Wu
Chia-Shan Hsieh
Yo-Cheng Chang
Chi-Cheng Huang
Hsien-Tang Yeh
Ming-Feng Hou
Yuan-Chiang Chung
Shih-Hsin Tu
King-Jen Chang
Amrita Chattopadhyay
Liang-Chuan Lai
Tzu-Pin Lu
Yung-Hua Li
Mong-Hsun Tsai
Eric Y. Chuang
author_sort Chia-Hsin Wu
title Differential whole-genome doubling and homologous recombination deficiencies across breast cancer subtypes from the Taiwanese population
title_short Differential whole-genome doubling and homologous recombination deficiencies across breast cancer subtypes from the Taiwanese population
title_full Differential whole-genome doubling and homologous recombination deficiencies across breast cancer subtypes from the Taiwanese population
title_fullStr Differential whole-genome doubling and homologous recombination deficiencies across breast cancer subtypes from the Taiwanese population
title_full_unstemmed Differential whole-genome doubling and homologous recombination deficiencies across breast cancer subtypes from the Taiwanese population
title_sort differential whole-genome doubling and homologous recombination deficiencies across breast cancer subtypes from the taiwanese population
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/21619eb086eb4dc1b61fe904c1ac2806
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