Differential whole-genome doubling and homologous recombination deficiencies across breast cancer subtypes from the Taiwanese population

Wu, Hsieh et al. analyze Taiwanese breast cancer patient samples using whole-exome sequencing to examine the heterogeneity and homogeneity in the timing and dependencies of somatic aberrations across disease subtypes. The authors focus on somatic alterations and related features that correlate with...

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Auteurs principaux:	Chia-Hsin Wu, Chia-Shan Hsieh, Yo-Cheng Chang, Chi-Cheng Huang, Hsien-Tang Yeh, Ming-Feng Hou, Yuan-Chiang Chung, Shih-Hsin Tu, King-Jen Chang, Amrita Chattopadhyay, Liang-Chuan Lai, Tzu-Pin Lu, Yung-Hua Li, Mong-Hsun Tsai, Eric Y. Chuang
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2021
Sujets:	Biology (General) QH301-705.5
Accès en ligne:	https://doaj.org/article/21619eb086eb4dc1b61fe904c1ac2806
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spelling	oai:doaj.org-article:21619eb086eb4dc1b61fe904c1ac28062021-12-02T17:19:12ZDifferential whole-genome doubling and homologous recombination deficiencies across breast cancer subtypes from the Taiwanese population10.1038/s42003-021-02597-x2399-3642https://doaj.org/article/21619eb086eb4dc1b61fe904c1ac28062021-09-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02597-xhttps://doaj.org/toc/2399-3642Wu, Hsieh et al. analyze Taiwanese breast cancer patient samples using whole-exome sequencing to examine the heterogeneity and homogeneity in the timing and dependencies of somatic aberrations across disease subtypes. The authors focus on somatic alterations and related features that correlate with whole genome doubling, including homologous recombination deficiencies.Chia-Hsin WuChia-Shan HsiehYo-Cheng ChangChi-Cheng HuangHsien-Tang YehMing-Feng HouYuan-Chiang ChungShih-Hsin TuKing-Jen ChangAmrita ChattopadhyayLiang-Chuan LaiTzu-Pin LuYung-Hua LiMong-Hsun TsaiEric Y. ChuangNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Chia-Hsin Wu Chia-Shan Hsieh Yo-Cheng Chang Chi-Cheng Huang Hsien-Tang Yeh Ming-Feng Hou Yuan-Chiang Chung Shih-Hsin Tu King-Jen Chang Amrita Chattopadhyay Liang-Chuan Lai Tzu-Pin Lu Yung-Hua Li Mong-Hsun Tsai Eric Y. Chuang Differential whole-genome doubling and homologous recombination deficiencies across breast cancer subtypes from the Taiwanese population
description	Wu, Hsieh et al. analyze Taiwanese breast cancer patient samples using whole-exome sequencing to examine the heterogeneity and homogeneity in the timing and dependencies of somatic aberrations across disease subtypes. The authors focus on somatic alterations and related features that correlate with whole genome doubling, including homologous recombination deficiencies.
format	article
author	Chia-Hsin Wu Chia-Shan Hsieh Yo-Cheng Chang Chi-Cheng Huang Hsien-Tang Yeh Ming-Feng Hou Yuan-Chiang Chung Shih-Hsin Tu King-Jen Chang Amrita Chattopadhyay Liang-Chuan Lai Tzu-Pin Lu Yung-Hua Li Mong-Hsun Tsai Eric Y. Chuang
author_facet	Chia-Hsin Wu Chia-Shan Hsieh Yo-Cheng Chang Chi-Cheng Huang Hsien-Tang Yeh Ming-Feng Hou Yuan-Chiang Chung Shih-Hsin Tu King-Jen Chang Amrita Chattopadhyay Liang-Chuan Lai Tzu-Pin Lu Yung-Hua Li Mong-Hsun Tsai Eric Y. Chuang
author_sort	Chia-Hsin Wu
title	Differential whole-genome doubling and homologous recombination deficiencies across breast cancer subtypes from the Taiwanese population
title_short	Differential whole-genome doubling and homologous recombination deficiencies across breast cancer subtypes from the Taiwanese population
title_full	Differential whole-genome doubling and homologous recombination deficiencies across breast cancer subtypes from the Taiwanese population
title_fullStr	Differential whole-genome doubling and homologous recombination deficiencies across breast cancer subtypes from the Taiwanese population
title_full_unstemmed	Differential whole-genome doubling and homologous recombination deficiencies across breast cancer subtypes from the Taiwanese population
title_sort	differential whole-genome doubling and homologous recombination deficiencies across breast cancer subtypes from the taiwanese population
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/21619eb086eb4dc1b61fe904c1ac2806
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Differential whole-genome doubling and homologous recombination deficiencies across breast cancer subtypes from the Taiwanese population

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