Isolation of Hox cluster genes from insects reveals an accelerated sequence evolution rate.

Among gene families it is the Hox genes and among metazoan animals it is the insects (Hexapoda) that have attracted particular attention for studying the evolution of development. Surprisingly though, no Hox genes have been isolated from 26 out of 35 insect orders yet, and the existing sequences der...

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Autores principales:	Heike Hadrys, Sabrina Simon, Barbara Kaune, Oliver Schmitt, Anja Schöner, Wolfgang Jakob, Bernd Schierwater
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2012
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/2161b189f33b4ba2a8dc63c66354b5a2
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spelling	oai:doaj.org-article:2161b189f33b4ba2a8dc63c66354b5a22021-11-18T07:16:07ZIsolation of Hox cluster genes from insects reveals an accelerated sequence evolution rate.1932-620310.1371/journal.pone.0034682https://doaj.org/article/2161b189f33b4ba2a8dc63c66354b5a22012-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22685537/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203Among gene families it is the Hox genes and among metazoan animals it is the insects (Hexapoda) that have attracted particular attention for studying the evolution of development. Surprisingly though, no Hox genes have been isolated from 26 out of 35 insect orders yet, and the existing sequences derive mainly from only two orders (61% from Hymenoptera and 22% from Diptera). We have designed insect specific primers and isolated 37 new partial homeobox sequences of Hox cluster genes (lab, pb, Hox3, ftz, Antp, Scr, abd-a, Abd-B, Dfd, and Ubx) from six insect orders, which are crucial to insect phylogenetics. These new gene sequences provide a first step towards comparative Hox gene studies in insects. Furthermore, comparative distance analyses of homeobox sequences reveal a correlation between gene divergence rate and species radiation success with insects showing the highest rate of homeobox sequence evolution.Heike HadrysSabrina SimonBarbara KauneOliver SchmittAnja SchönerWolfgang JakobBernd SchierwaterPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 7, Iss 6, p e34682 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Heike Hadrys Sabrina Simon Barbara Kaune Oliver Schmitt Anja Schöner Wolfgang Jakob Bernd Schierwater Isolation of Hox cluster genes from insects reveals an accelerated sequence evolution rate.
description	Among gene families it is the Hox genes and among metazoan animals it is the insects (Hexapoda) that have attracted particular attention for studying the evolution of development. Surprisingly though, no Hox genes have been isolated from 26 out of 35 insect orders yet, and the existing sequences derive mainly from only two orders (61% from Hymenoptera and 22% from Diptera). We have designed insect specific primers and isolated 37 new partial homeobox sequences of Hox cluster genes (lab, pb, Hox3, ftz, Antp, Scr, abd-a, Abd-B, Dfd, and Ubx) from six insect orders, which are crucial to insect phylogenetics. These new gene sequences provide a first step towards comparative Hox gene studies in insects. Furthermore, comparative distance analyses of homeobox sequences reveal a correlation between gene divergence rate and species radiation success with insects showing the highest rate of homeobox sequence evolution.
format	article
author	Heike Hadrys Sabrina Simon Barbara Kaune Oliver Schmitt Anja Schöner Wolfgang Jakob Bernd Schierwater
author_facet	Heike Hadrys Sabrina Simon Barbara Kaune Oliver Schmitt Anja Schöner Wolfgang Jakob Bernd Schierwater
author_sort	Heike Hadrys
title	Isolation of Hox cluster genes from insects reveals an accelerated sequence evolution rate.
title_short	Isolation of Hox cluster genes from insects reveals an accelerated sequence evolution rate.
title_full	Isolation of Hox cluster genes from insects reveals an accelerated sequence evolution rate.
title_fullStr	Isolation of Hox cluster genes from insects reveals an accelerated sequence evolution rate.
title_full_unstemmed	Isolation of Hox cluster genes from insects reveals an accelerated sequence evolution rate.
title_sort	isolation of hox cluster genes from insects reveals an accelerated sequence evolution rate.
publisher	Public Library of Science (PLoS)
publishDate	2012
url	https://doaj.org/article/2161b189f33b4ba2a8dc63c66354b5a2
work_keys_str_mv	AT heikehadrys isolationofhoxclustergenesfrominsectsrevealsanacceleratedsequenceevolutionrate AT sabrinasimon isolationofhoxclustergenesfrominsectsrevealsanacceleratedsequenceevolutionrate AT barbarakaune isolationofhoxclustergenesfrominsectsrevealsanacceleratedsequenceevolutionrate AT oliverschmitt isolationofhoxclustergenesfrominsectsrevealsanacceleratedsequenceevolutionrate AT anjaschoner isolationofhoxclustergenesfrominsectsrevealsanacceleratedsequenceevolutionrate AT wolfgangjakob isolationofhoxclustergenesfrominsectsrevealsanacceleratedsequenceevolutionrate AT berndschierwater isolationofhoxclustergenesfrominsectsrevealsanacceleratedsequenceevolutionrate
_version_	1718423649516519424

Isolation of Hox cluster genes from insects reveals an accelerated sequence evolution rate.

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