Manifold learning analysis suggests strategies to align single-cell multimodal data of neuronal electrophysiology and transcriptomics

Huang et al apply and benchmark multiple machine learning methods to align gene expression and electrophysiological data of single neuronal cells in the mouse brain from the Brain Initiative. Their approach reveals potential genome functions and gene regulatory mechanisms from gene expression to neu...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Jiawei Huang, Jie Sheng, Daifeng Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/216380d4edf44c03beae98a5f0ad5b06
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:216380d4edf44c03beae98a5f0ad5b06
record_format	dspace
spelling	oai:doaj.org-article:216380d4edf44c03beae98a5f0ad5b062021-11-21T12:08:27ZManifold learning analysis suggests strategies to align single-cell multimodal data of neuronal electrophysiology and transcriptomics10.1038/s42003-021-02807-62399-3642https://doaj.org/article/216380d4edf44c03beae98a5f0ad5b062021-11-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02807-6https://doaj.org/toc/2399-3642Huang et al apply and benchmark multiple machine learning methods to align gene expression and electrophysiological data of single neuronal cells in the mouse brain from the Brain Initiative. Their approach reveals potential genome functions and gene regulatory mechanisms from gene expression to neuronal electrophysiology.Jiawei HuangJie ShengDaifeng WangNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Jiawei Huang Jie Sheng Daifeng Wang Manifold learning analysis suggests strategies to align single-cell multimodal data of neuronal electrophysiology and transcriptomics
description	Huang et al apply and benchmark multiple machine learning methods to align gene expression and electrophysiological data of single neuronal cells in the mouse brain from the Brain Initiative. Their approach reveals potential genome functions and gene regulatory mechanisms from gene expression to neuronal electrophysiology.
format	article
author	Jiawei Huang Jie Sheng Daifeng Wang
author_facet	Jiawei Huang Jie Sheng Daifeng Wang
author_sort	Jiawei Huang
title	Manifold learning analysis suggests strategies to align single-cell multimodal data of neuronal electrophysiology and transcriptomics
title_short	Manifold learning analysis suggests strategies to align single-cell multimodal data of neuronal electrophysiology and transcriptomics
title_full	Manifold learning analysis suggests strategies to align single-cell multimodal data of neuronal electrophysiology and transcriptomics
title_fullStr	Manifold learning analysis suggests strategies to align single-cell multimodal data of neuronal electrophysiology and transcriptomics
title_full_unstemmed	Manifold learning analysis suggests strategies to align single-cell multimodal data of neuronal electrophysiology and transcriptomics
title_sort	manifold learning analysis suggests strategies to align single-cell multimodal data of neuronal electrophysiology and transcriptomics
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/216380d4edf44c03beae98a5f0ad5b06
work_keys_str_mv	AT jiaweihuang manifoldlearninganalysissuggestsstrategiestoalignsinglecellmultimodaldataofneuronalelectrophysiologyandtranscriptomics AT jiesheng manifoldlearninganalysissuggestsstrategiestoalignsinglecellmultimodaldataofneuronalelectrophysiologyandtranscriptomics AT daifengwang manifoldlearninganalysissuggestsstrategiestoalignsinglecellmultimodaldataofneuronalelectrophysiologyandtranscriptomics
_version_	1718419173300764672

Manifold learning analysis suggests strategies to align single-cell multimodal data of neuronal electrophysiology and transcriptomics

Ejemplares similares