Chronic Fatigue Syndrome: A Case Report Highlighting Diagnosing and Treatment Challenges and the Possibility of Jarisch–Herxheimer Reactions If High Infectious Loads Are Present

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex multi-system disease with no cure and no FDA-approved treatment. Approximately 25% of patients are house or bedbound, and some are so severe in function that they require tube-feeding and are unable to tolerate light, sound, an...

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Autores principales:	Rachel K. Straub, Christopher M. Powers
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	myalgic encephalomyelitis (ME) chronic fatigue syndrome (CFS) post-exertional malaise die-off reactions chronic illness Lyme disease Medicine R
Acceso en línea:	https://doaj.org/article/21684592fca94904b256d0ae6e1e8e08
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spelling	oai:doaj.org-article:21684592fca94904b256d0ae6e1e8e082021-11-25T17:45:49ZChronic Fatigue Syndrome: A Case Report Highlighting Diagnosing and Treatment Challenges and the Possibility of Jarisch–Herxheimer Reactions If High Infectious Loads Are Present10.3390/healthcare91115372227-9032https://doaj.org/article/21684592fca94904b256d0ae6e1e8e082021-11-01T00:00:00Zhttps://www.mdpi.com/2227-9032/9/11/1537https://doaj.org/toc/2227-9032Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex multi-system disease with no cure and no FDA-approved treatment. Approximately 25% of patients are house or bedbound, and some are so severe in function that they require tube-feeding and are unable to tolerate light, sound, and human touch. The overall goal of this case report was to (1) describe how past events (e.g., chronic sinusitis, amenorrhea, tick bites, congenital neutropenia, psychogenic polydipsia, food intolerances, and hypothyroidism) may have contributed to the development of severe ME/CFS in a single patient, and (2) the extensive medical interventions that the patient has pursued in an attempt to recover, which enabled her to return to graduate school after becoming bedridden with ME/CFS 4.5 years prior. This paper aims to increase awareness of the harsh reality of ME/CFS and the potential complications following initiation of any level of intervention, some of which may be necessary for long-term healing. Treatments may induce severe paradoxical reactions (Jarisch–Herxheimer reaction) if high infectious loads are present. It is our hope that sharing this case will improve research and treatment options for ME/CFS.Rachel K. StraubChristopher M. PowersMDPI AGarticlemyalgic encephalomyelitis (ME)chronic fatigue syndrome (CFS)post-exertional malaisedie-off reactionschronic illnessLyme diseaseMedicineRENHealthcare, Vol 9, Iss 1537, p 1537 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	myalgic encephalomyelitis (ME) chronic fatigue syndrome (CFS) post-exertional malaise die-off reactions chronic illness Lyme disease Medicine R
spellingShingle	myalgic encephalomyelitis (ME) chronic fatigue syndrome (CFS) post-exertional malaise die-off reactions chronic illness Lyme disease Medicine R Rachel K. Straub Christopher M. Powers Chronic Fatigue Syndrome: A Case Report Highlighting Diagnosing and Treatment Challenges and the Possibility of Jarisch–Herxheimer Reactions If High Infectious Loads Are Present
description	Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex multi-system disease with no cure and no FDA-approved treatment. Approximately 25% of patients are house or bedbound, and some are so severe in function that they require tube-feeding and are unable to tolerate light, sound, and human touch. The overall goal of this case report was to (1) describe how past events (e.g., chronic sinusitis, amenorrhea, tick bites, congenital neutropenia, psychogenic polydipsia, food intolerances, and hypothyroidism) may have contributed to the development of severe ME/CFS in a single patient, and (2) the extensive medical interventions that the patient has pursued in an attempt to recover, which enabled her to return to graduate school after becoming bedridden with ME/CFS 4.5 years prior. This paper aims to increase awareness of the harsh reality of ME/CFS and the potential complications following initiation of any level of intervention, some of which may be necessary for long-term healing. Treatments may induce severe paradoxical reactions (Jarisch–Herxheimer reaction) if high infectious loads are present. It is our hope that sharing this case will improve research and treatment options for ME/CFS.
format	article
author	Rachel K. Straub Christopher M. Powers
author_facet	Rachel K. Straub Christopher M. Powers
author_sort	Rachel K. Straub
title	Chronic Fatigue Syndrome: A Case Report Highlighting Diagnosing and Treatment Challenges and the Possibility of Jarisch–Herxheimer Reactions If High Infectious Loads Are Present
title_short	Chronic Fatigue Syndrome: A Case Report Highlighting Diagnosing and Treatment Challenges and the Possibility of Jarisch–Herxheimer Reactions If High Infectious Loads Are Present
title_full	Chronic Fatigue Syndrome: A Case Report Highlighting Diagnosing and Treatment Challenges and the Possibility of Jarisch–Herxheimer Reactions If High Infectious Loads Are Present
title_fullStr	Chronic Fatigue Syndrome: A Case Report Highlighting Diagnosing and Treatment Challenges and the Possibility of Jarisch–Herxheimer Reactions If High Infectious Loads Are Present
title_full_unstemmed	Chronic Fatigue Syndrome: A Case Report Highlighting Diagnosing and Treatment Challenges and the Possibility of Jarisch–Herxheimer Reactions If High Infectious Loads Are Present
title_sort	chronic fatigue syndrome: a case report highlighting diagnosing and treatment challenges and the possibility of jarisch–herxheimer reactions if high infectious loads are present
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/21684592fca94904b256d0ae6e1e8e08
work_keys_str_mv	AT rachelkstraub chronicfatiguesyndromeacasereporthighlightingdiagnosingandtreatmentchallengesandthepossibilityofjarischherxheimerreactionsifhighinfectiousloadsarepresent AT christophermpowers chronicfatiguesyndromeacasereporthighlightingdiagnosingandtreatmentchallengesandthepossibilityofjarischherxheimerreactionsifhighinfectiousloadsarepresent
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Chronic Fatigue Syndrome: A Case Report Highlighting Diagnosing and Treatment Challenges and the Possibility of Jarisch–Herxheimer Reactions If High Infectious Loads Are Present

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