The ERK-1 function is required for HSV-1-mediated G1/S progression in HEP-2 cells and contributes to virus growth

The ERK-1 function is required for HSV-1-mediated G1/S progression in HEP-2 cells and contributes to virus growth

Abstract The herpes simplex virus 1 is able to readdress different cellular pathways including cell cycle to facilitate its replication and spread. During infection, the progression of the cell cycle from G1 to S phase makes the cellular replication machinery accessible to viral DNA replication. In...

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Autores principales: Ivana Colao, Rosamaria Pennisi, Assunta Venuti, Michaela Nygårdas, Outi Heikkilä, Veijo Hukkanen, Maria Teresa Sciortino
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/217a1b8760994f5d85cc707e7a290789
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