A systematic exploration of the interactions between bacterial effector proteins and host cell membranes

Microbial pathogens secrete effector proteins into host cells to affect cellular functions. Here, the authors use a yeast-based screen to study around 200 effectors from six bacterial species, showing that over 30% of them interact with the eukaryotic plasma membrane or intracellular organelles.

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Auteurs principaux:	Bethany A. Weigele, Robert C. Orchard, Alyssa Jimenez, Gregory W. Cox, Neal M. Alto
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2017
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/217bfd32a26b4c0bb9b8f8ae3db9c3fe
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id	oai:doaj.org-article:217bfd32a26b4c0bb9b8f8ae3db9c3fe
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spelling	oai:doaj.org-article:217bfd32a26b4c0bb9b8f8ae3db9c3fe2021-12-02T14:42:11ZA systematic exploration of the interactions between bacterial effector proteins and host cell membranes10.1038/s41467-017-00700-72041-1723https://doaj.org/article/217bfd32a26b4c0bb9b8f8ae3db9c3fe2017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00700-7https://doaj.org/toc/2041-1723Microbial pathogens secrete effector proteins into host cells to affect cellular functions. Here, the authors use a yeast-based screen to study around 200 effectors from six bacterial species, showing that over 30% of them interact with the eukaryotic plasma membrane or intracellular organelles.Bethany A. WeigeleRobert C. OrchardAlyssa JimenezGregory W. CoxNeal M. AltoNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Bethany A. Weigele Robert C. Orchard Alyssa Jimenez Gregory W. Cox Neal M. Alto A systematic exploration of the interactions between bacterial effector proteins and host cell membranes
description	Microbial pathogens secrete effector proteins into host cells to affect cellular functions. Here, the authors use a yeast-based screen to study around 200 effectors from six bacterial species, showing that over 30% of them interact with the eukaryotic plasma membrane or intracellular organelles.
format	article
author	Bethany A. Weigele Robert C. Orchard Alyssa Jimenez Gregory W. Cox Neal M. Alto
author_facet	Bethany A. Weigele Robert C. Orchard Alyssa Jimenez Gregory W. Cox Neal M. Alto
author_sort	Bethany A. Weigele
title	A systematic exploration of the interactions between bacterial effector proteins and host cell membranes
title_short	A systematic exploration of the interactions between bacterial effector proteins and host cell membranes
title_full	A systematic exploration of the interactions between bacterial effector proteins and host cell membranes
title_fullStr	A systematic exploration of the interactions between bacterial effector proteins and host cell membranes
title_full_unstemmed	A systematic exploration of the interactions between bacterial effector proteins and host cell membranes
title_sort	systematic exploration of the interactions between bacterial effector proteins and host cell membranes
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/217bfd32a26b4c0bb9b8f8ae3db9c3fe
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A systematic exploration of the interactions between bacterial effector proteins and host cell membranes

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