Callyspongiolide kills cells by inducing mitochondrial dysfunction via cellular iron depletion
In order to elucidate how callyspongiolide, a potent cytotoxic marine natural product, kills human lung cancer cells, Ha and Park employed TS-FITGE technique, a label-free target identification method with thermal stability-shift-based fluorescence difference in 2-D gel electrophoresis, allowing the...
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Main Authors: | Jaeyoung Ha, Seung Bum Park |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Online Access: | https://doaj.org/article/21861e7f52244f70ac8f9eb09ea4dba8 |
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