Callyspongiolide kills cells by inducing mitochondrial dysfunction via cellular iron depletion

In order to elucidate how callyspongiolide, a potent cytotoxic marine natural product, kills human lung cancer cells, Ha and Park employed TS-FITGE technique, a label-free target identification method with thermal stability-shift-based fluorescence difference in 2-D gel electrophoresis, allowing the...

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Bibliographic Details
Main Authors: Jaeyoung Ha, Seung Bum Park
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/21861e7f52244f70ac8f9eb09ea4dba8
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